Results 141 to 150 of about 33,241,813 (298)
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
reservedRapid technological developments are redefining what it means to be a data-driven company. Today, organizations are using sporadically Artificial Intelligence (AI) and Business Intelligence (BI) to predict trends and uncover insights, based on ...
BADARAU, ADRIAN
core
On the linear quadratic data-driven control
, 2007 The classical approach for solving control problems is model based: first a model representation is derived from given data of the plant and then a control law is synthesized using the model and the control specifications.
Paolo Rapisarda +3 more
core +1 more source
Molecular Oncology, EarlyView.RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
Data Driven Design for PSS (Product Re-design Based on Previous Knowledge)
The use of data-driven techniques can support the trade-off between different PSS design concepts by allowing dynamic indexing and retrieval of information to detect correlations and emerging trends. The chapter presents a data-driven approach exploiting
Bertoni, Alessandro,
core +1 more source
Kinetic data-driven approach to turbulence subgrid modeling
Physical Review ResearchNumerical simulations of turbulent flows are well known to pose extreme computational challenges because of the huge number of dynamical degrees of freedom required to correctly describe the complex multiscale statistical correlations of the velocity. On
G. Ortali +4 more
doaj +1 more source
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Two-Hemisphere Model Driven Approach: Engineering Based Software Development
Several model driven approaches are currently used and developed, namely, generic model driven approaches, agile model driven approaches, business process model driven approaches, etc.
Ņikiforova, Oksana, Kirikova, Mārīte
core
Data-driven Approach to Aesthetic Enhancement
Electronic Imaging, 2016 Jihye Choi +4 more
openaire +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source