Results 111 to 120 of about 2,992,402 (305)

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

Dynamic data flow testing [PDF]

open access: yes, 2016
Data flow testing is a particular form of testing that identifies data flow relations as test objectives. Data flow testing has recently attracted new interest in the context of testing object oriented systems, since data flow information is well ...
Pezzè, Mauro, Vivanti, Mattia
core  

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Commuting flow prediction using OpenStreetMap data

open access: yesComputational Urban Science
Accurately predicting commuting flows is crucial for sustainable urban planning and preventing disease spread due to human mobility. While recent advancements have produced effective models for predicting these recurrent flows, the existing methods rely ...
Kuldip Singh Atwal   +3 more
doaj   +1 more source

Data flow within global clinical trials: a scoping review. [PDF]

open access: yesBMJ Glob Health, 2022
Kwok K, Sati N, Dron L, Murthy S.
europepmc   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Globally Conditioned Conditional FLOW (GCC-FLOW) for Sea Clutter Data Augmentation

open access: yesApplied Sciences
In this paper, a novel deep learning approach based on conditional FLOW is proposed for sea clutter augmentation. Sea clutter data augmentation is important for testing detection algorithms for maritime remote sensing and surveillance due to the ...
Seokwon Lee, Wonzoo Chung
doaj   +1 more source

Home - About - Disclaimer - Privacy