Results 171 to 180 of about 2,992,402 (305)

Data Flow-Based Strategies to Improve the Interpretation and Understanding of Machine Learning Models. [PDF]

Bioengineering (Basel)
Brimacombe M.
europepmc   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source

Sustainable management of family life and finance in the context of digital capabilities - data flow dynamics. [PDF]

Heliyon
Liu J, Khan M, Liu F.
europepmc   +1 more source

Acoustic Sensor Data Flow for Cultural Heritage Monitoring and Safeguarding. [PDF]

Sensors (Basel), 2019
Kasnesis P, Tatlas NA, Mitilineos SA, Patrikakis CZ, Potirakis SM.   +4 more
europepmc   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Navigating the network: a narrative overview of AMR surveillance and data flow in the United States. [PDF]

Antimicrob Steward Healthc Epidemiol
Robillard DW, Sundermann AJ, Raux BR, Prinzi AM.   +3 more
europepmc   +1 more source

Anomaly Detection Based Latency-Aware Energy Consumption Optimization For IoT Data-Flow Services. [PDF]

Sensors (Basel), 2019
Luo Y, Li W, Qiu S.
europepmc   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Limiting heterogeneity in cross-border data flow: Impact on domestic value chains stability and the role of innovation. [PDF]

PLoS One
Liu Y, Zhang Y, Jiang R, Cheng J, Dai J.
europepmc   +1 more source