Results 191 to 200 of about 63,638,251 (398)

S_4 Flavor Symmetry Embedded into SU(3) and Lepton Masses and Mixing

open access: yes, 2007
Based on an assumption that an S_4 flavor symmetry is embedded into SU(3), a lepton mass matrix model is investigated. A Frogatt-Nielsen type model is assumed, and the flavor structures of the masses and mixing are caused by VEVs of SU(2)_L-singlet ...
C. Hagedorn   +4 more
core   +1 more source

Cell‐free and extracellular vesicle microRNAs with clinical utility for solid tumors

open access: yesMolecular Oncology, EarlyView.
Cell‐free microRNAs (cfmiRs) are small‐RNA circulating molecules detectable in almost all body biofluids. Innovative technologies have improved the application of cfmiRs to oncology, with a focus on clinical needs for different solid tumors, but with emphasis on diagnosis, prognosis, cancer recurrence, as well as treatment monitoring.
Yoshinori Hayashi   +6 more
wiley   +1 more source

Integrating single-cell transcriptomic data across different conditions, technologies, and species

open access: yesNature Biotechnology, 2018
Andrew Butler   +4 more
semanticscholar   +1 more source

Regularizing the quark-level $\sigma$ model

open access: yes, 1998
We show that the finite difference, $-i\pi^2 m^2$, between quadratic and logarithmic divergent integrals $\int d^4p[m^2(p^2-m^2)^{-2}-(p^2-m^2)^{-1}]$, as encountered in the linear $\sigma$ model, is in fact regularization independent.Comment: 9 pages, 2
A. A. RAWLINSON   +3 more
core   +1 more source

KRAS and GNAS mutations in cell‐free DNA and in circulating epithelial cells in patients with intraductal papillary mucinous neoplasms—an observational pilot study

open access: yesMolecular Oncology, EarlyView.
This study demonstrates that KRAS and GNAS mutations are more prevalent in patients with resected intraductal papillary mucinous neoplasms (IPMN) compared to those under clinical surveillance. GNAS mutations significantly differ between the two patient cohorts, indicating that their absence may serve as a potential biomarker to support conservative ...
Christine Nitschke   +12 more
wiley   +1 more source

Cellular liquid biopsy provides unique chances for disease monitoring, preclinical model generation and therapy adjustment in rare salivary gland cancer patients

open access: yesMolecular Oncology, EarlyView.
We quantified and cultured circulating tumor cells (CTCs) of 62 patients with various cancer types and generated CTC‐derived tumoroid models from two salivary gland cancer patients. Cellular liquid biopsy‐derived information enabled molecular genetic assessment of systemic disease heterogeneity and functional testing for therapy selection in both ...
Nataša Stojanović Gužvić   +31 more
wiley   +1 more source

Combined spatially resolved metabolomics and spatial transcriptomics reveal the mechanism of RACK1‐mediated fatty acid synthesis

open access: yesMolecular Oncology, EarlyView.
The authors analyzed the spatial distributions of gene and metabolite profiles in cervical cancer through spatial transcriptomic and spatially resolved metabolomic techniques. Pivotal genes and metabolites within these cases were then identified and validated.
Lixiu Xu   +3 more
wiley   +1 more source

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