Results 281 to 290 of about 63,638,251 (398)

Revisiting In-Gas Transformations of Quinate Conjugates Through the LC-qTOF-MS and Molecular Networking Topology. [PDF]

Rapid Commun Mass Spectrom
Moyo NB, Madala NE.
europepmc   +1 more source

Targeting the MDM2‐MDM4 interaction interface reveals an otherwise therapeutically active wild‐type p53 in colorectal cancer

Molecular Oncology, EarlyView.
This study investigates an alternative approach to reactivating the oncosuppressor p53 in cancer. A short peptide targeting the association of the two p53 inhibitors, MDM2 and MDM4, induces an otherwise therapeutically active p53 with unique features that promote cell death and potentially reduce toxicity towards proliferating nontumor cells.
Sonia Valentini, Giada Mele, Marika Attili, Maria Rita Assenza, Fulvio Saccoccia, Francesca Sardina, Cinzia Rinaldo, Roberto Massari, Nicola Tirelli, Alfredo Pontecorvi, Fabiola Moretti   +10 more
wiley   +1 more source

Record of family faculties; consisting of tabular forms and directions for entering data, with an explanatory pref

, 1884
Francis Galton
openalex   +2 more sources

The future of electronic health record-based research: Leveraging informatics in genetic counseling research. [PDF]

J Genet Couns
Greenberg SE, Reys B, Fisher H, Basit M.
europepmc   +1 more source

Thermal proteome profiling and proteome analysis using high‐definition mass spectrometry demonstrate modulation of cholesterol biosynthesis by next‐generation galeterone analog VNPP433‐3β in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Elevated level of cholesterol is positively correlated to prostate cancer development and disease severity. Cholesterol‐lowering drugs, such as statins, are demonstrated to inhibit prostate cancer. VNPP433‐3β interrupts multiple signaling and metabolic pathways, including cholesterol biosynthesis, AR‐mediated transcription of several oncogenes, mRNA 5′
Retheesh S. Thankan, Elizabeth Thomas, Mehari M. Weldemariam, Puranik Purushottamachar, Weiliang Huang, Maureen A. Kane, Yuji Zhang, Nicholas Ambulos, Bi‐Dar Wang, David Weber, Vincent C. O. Njar   +10 more
wiley   +1 more source

Contributions to our Knowledge of the Plankton of the Faeroe Channel.1–No. VII. A. General Data of the Stations. B. The Protozoa. C. The Medusæ.

, 1898
Herbert Fowler
openalex   +2 more sources

Data on Platinum Gauze Used as.a Catalyzer for the Oxidation of Ammonia. Table of Weights and Active Surface of Platinum, Air Space, Etc., Shown for a Unit of One Square Inch of Gauze of a Given Mesh and Diameter of Wire. [PDF]

, 1919
Alvin Allen Campbell
openalex   +1 more source

Pain Assessment and Its Effect on Pain Management During Emergency Medical Services-A Descriptive Study in the Tampere University Hospital Area of Finland. [PDF]

Acta Anaesthesiol Scand
Lidauer SM, Hoppu S, Kaartinen K, Lidauer MH, Kalliomäki ML.   +4 more
europepmc   +1 more source

Elucidating prognostic significance of purine metabolism in colorectal cancer through integrating data from transcriptomic, immunohistochemical, and single‐cell RNA sequencing analysis

Molecular Oncology, EarlyView.
Low expression of five purine metabolism‐related genes (ADSL, APRT, ADCY3, NME3, NME6) was correlated with poor survival in colorectal cancer. Immunohistochemistry analysis showed that low NME3 (early stage) and low ADSL/NME6 (late stage) levels were associated with high risk.
Sungyeon Kim, Myunghee Kang, Soyeon Jeong, Jisup Kim, Kyoung Oh Kim, Won‐Suk Lee, Jeong‐Heum Baek, Jung Ho Kim, Seungyoon Nam   +8 more
wiley   +1 more source

New Data on the Ultrachondrioma

, 1954
Judith Harel, C Oberling
openalex   +1 more source