Results 321 to 330 of about 66,190,054 (394)

Global lessons from local contexts: The evolution of biomedicine education in Spain. [PDF]

PLoS One
Muñoz FJ, Esteban E, Pérez-Mediavilla A, Capitán L.   +3 more
europepmc   +1 more source

The influence of ROS1 fusion partners and resistance mechanisms in ROS1‐TKI‐treated non‐small cell lung cancer patients

Molecular Oncology, EarlyView.
This real‐world study of ROS1+ NSCLC highlights fusion diversity, treatment outcomes with crizotinib and lorlatinib, and in vitro experiments with resistance mechanisms. G2032R drives strong resistance to ROS1‐targeted TKIs, especially lorlatinib. Fusion partner location does not affect overall survival to crizotinib or lorlatinib. Findings support the
Fenneke Zwierenga, Christa Dijkhuizen, Patrick Korthuis, Wim Timens, Harry Groen, Jeroen Hiltermann, Anke van den Berg, Lyndsay Drayer, Anthonie van der Wekken   +8 more
wiley   +1 more source

Bridging climate and health data for decision making. [PDF]

BMC Proc
Mikhailov D, Chunara R, Cucunubá Z, Lamarque JF, Lennard C, Stewart U.   +5 more
europepmc   +1 more source

YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma

Molecular Oncology, EarlyView.
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy, Samuel Hartzler, Paula A. Vargas Carranza, Shyaman Jayasundara, Madison E. Yates, Nimod D. Janson, Bozhi Liu, Annaleigh Benton, Majid Kazemian, Jason A. Hanna   +9 more
wiley   +1 more source

MR elastography datasets including phantom, liver, and brain. [PDF]

Sci Data
Feng Y, Qiu S, Wang R, Ma S, Yan F, Yang GZ.   +5 more
europepmc   +1 more source

Oceanographic Conditions in the Northwestern North Pacific based upon the data obtained on board the “Komahashi” from 1934 to 1936

, 1958
Jiro SUGIURA
openalex   +2 more sources

Emerging role of ARHGAP29 in melanoma cell phenotype switching

Molecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster, Melanie Kappelmann‐Fenzl, Anja Katrin Bosserhoff, Nicole Rachinger   +3 more
wiley   +1 more source

GlASS - Global Aggregation of Stream Silica. [PDF]

Sci Data
Jankowski KJ, Johnson K, Lyon NJ, Bush SA, Julian P, Sethna LR, McKnight DM, McDowell WH, Wymore AS, Kortelainen P, Laudon H, Heindel RC, Poste AE, Shogren A, Worral F, Mosley L, Sullivan PL, Carey JC.   +17 more
europepmc   +1 more source

Tumor‐agnostic detection of circulating tumor DNA in patients with advanced pancreatic cancer using targeted DNA methylation sequencing and cell‐free DNA fragmentomics

Molecular Oncology, EarlyView.
We evaluated circulating tumor DNA (ctDNA) detection in advanced pancreatic cancer using DNA methylation, cell‐free DNA fragment lengths, and 5′ end motifs. Machine learning models were trained to estimate ctDNA levels from each feature and their combination.
Morten Lapin, Kjersti Tjensvoll, Karin Hestnes Edland, Satu Oltedal, Herish Garresori, Bjørnar Gilje, Saga Ekedal, Trygve Eftestøl, Jan Terje Kvaløy, Filip Janku, Oddmund Nordgård   +10 more
wiley   +1 more source

Box-meter integrated solution for power data imputation through device design and deep learning integration. [PDF]

Sci Rep
Gao C, Lin H, Lin Y.
europepmc   +1 more source