Results 91 to 100 of about 12,309,063 (288)

IVOA Recommendation: Simple Spectral Access Protocol Version 1.1

, 2012
The Simple Spectral Access (SSA) Protocol (SSAP) defines a uniform interface to remotely discover and access one dimensional spectra. SSA is a member of an integrated family of data access interfaces altogether comprising the Data Access Layer (DAL) of ...
Bonnarel, Francois, Budavari, Tamas, Busko, Ivo, Dolensky, Markus, group, the Data Access Layer working, McDowell, Jonathan, Micol, Alberto, Osuna, Pedro, Salgado, Jesus, Skoda, Petr, Thompson, Randy, Tody, Doug, Valdes, Frank   +12 more
core   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Black Phosphorus-Film with Drop-Casting Method for High-Energy Pulse Generation From Q-Switched Er-Doped Fiber Laser

Photonic Sensors, 2019
We have reported high-energy pulse generation from a Q-switched Er-doped fiber laser based on black phosphorus (BP) with a drop-casting method. Poly dimethyl diallyl ammonium (PDDA) is employed to protect BP.
Huanhuan Liu, Wei Song, Ye Yu, Qiao Jiang, Fufei Pang, Tingyun Wang   +5 more
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Spectrally Flat Supercontinuum Generation in a ZBLAN Fiber Pumped by Erbium-Doped Mode-Locked Fiber Laser

Photonic Sensors, 2019
We have experimentally demonstrated the flat supercontinuum (SC) generation using a 10-m-long ZrF4-BaF2-LaF3-AlF3-NaF (ZBLAN) fluoride fiber pumped by an erbium-doped mode-locked fiber laser incorporating carbon-nanotube-based saturable absorbers.
Huanhuan Liu, Ye Yu, Wei Song, Qiao Jiang, Fufei Pang, Tingyun Wang   +5 more
doaj   +1 more source

Random Pilot and Data Access in Massive MIMO for Machine-type Communications

, 2017
A massive MIMO system, represented by a base station with hundreds of antennas, is capable of spatially multiplexing many devices and thus naturally suited to serve dense crowds of wireless devices in emerging applications, such as machine-type ...
Björnson, Emil, de Carvalho, Elisabeth, Larsson, Erik G., Popovski, Petar, Sørensen, Jesper H.   +4 more
core   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

FEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang, Satoshi Hashimoto, Sota Ito, Chisato Kikuguchi, Miho Hoshi, Kiyoshi Yamaguchi, Yoichi Furukawa, Toru Suzuki, Toshifumi Inada   +8 more
wiley   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source

Economic and Medical Burden of Non-Exudative Age-Related Macular Degeneration in Germany: A Retrospective Observational Claims Data Study

Clinical Ophthalmology
Alexander K Schuster,1 Lilia Leisle,2 Nils Picker,2 Hanne Vorwerk,3 Philipp Hahn,4 Jürgen Wasem,5 Philip Lewis3 1Department of Ophthalmology, University Medical Center Mainz, Mainz, Germany; 2Evidence, Value & Access, Cytel, Berlin, Germany; 3Apellis
Schuster AK, Leisle L, Picker N, Vorwerk H, Hahn P, Wasem J, Lewis P   +6 more
doaj