Results 41 to 50 of about 2,448,996 (248)

Comprehensive Stroke Centers May Be Associated With Improved Survival in Hemorrhagic Stroke

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2015
Background Comprehensive stroke centers (CSCs) provide a full spectrum of neurological and neurosurgical services to treat complex stroke patients. CSCs have been shown to improve clinical outcomes and mitigate disparities in ischemic stroke patients. It
James S. McKinney, Jerry Q. Cheng, Igor Rybinnik, John B. Kostis, the Myocardial Infarction Data Acquisition System (MIDAS 22) Study Group   +4 more
doaj   +1 more source

LUOJIA Explorer PMS: Panoramic Odometry and Mapping with Structural Information [PDF]

The International Archives of the Photogrammetry, Remote Sensing and Spatial Information Sciences
Accurate dense reconstruction of unknown spatial environments is crucial for applications such as underground exploration and planetary missions. Existing methods face challenges like observing blind spots and the difficulty of edge feature extraction in
Y. Xu, Y. Xu, Y. Xu, C. Chen, C. Chen, C. Chen, B. Yang, B. Yang, B. Yang, L. Li, Z. Wang, Z. Wang, Z. Wang, S. Sun, S. Sun, S. Sun, Z. Yan, Z. Yan, Z. Yan, S. Wu, S. Wu, S. Wu   +21 more
doaj   +1 more source

Assessment of Performance, Interpretability, and Explainability in Artificial Intelligence–Based Health Technologies: What Healthcare Stakeholders Need to Know

Mayo Clinic Proceedings: Digital Health, 2023
This review aimed to specify different concepts that are essential to the development of medical devices (MDs) with artificial intelligence (AI) (AI-based MDs) and shed light on how algorithm performance, interpretability, and explainability are key ...
Line Farah, PharmD, Juliette M. Murris, MSc, Isabelle Borget, PhD, PharmD, Agathe Guilloux, PhD, Nicolas M. Martelli, PhD, PharmD, Sandrine I.M. Katsahian, MD, PhD   +5 more
doaj   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source

Energy Consumption-Driven UAV Dock Deployment Planning for Power Inspection [PDF]

The International Archives of the Photogrammetry, Remote Sensing and Spatial Information Sciences
As an important energy in modern society, the stable operation of electricity is the guarantee of social and economic operation, and the loss caused by the damage of power facilities is immeasurable, so the regular monitoring of power facilities is ...
J. Fu, G. Shao, Z. Wang, Z. Wang, Z. Wang, S. Wu, S. Wu, S. Wu, H. Cai, H. Wu, C. Chen, C. Chen, C. Chen, B. Yang, B. Yang, B. Yang   +15 more
doaj   +1 more source

Routing Protocol of Underwater Wireless Sensor Network Based on Vector and Energy [PDF]

Jisuanji gongcheng, 2018
Underwater Wireless Sensor Network(WSN) has the characteristics of high energy consumption,low efficiency of data transmission,dynamic topology.Aiming at the mobility advantage of nodes in the underwater environment,this paper puts forward a Vector and ...
ZHANG Jianan,DU Xiujuan,LI Meiju,WANG Lijuan
doaj   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source