Results 161 to 170 of about 50,356,783 (293)

massMatchR: a Shiny application for glycomics mass spectrometry data analysis. [PDF]

Bioinformatics
Beke G, Kl'učár L, Pakanová Z, Kodríkova R, Baráth P, Nemčovič M.   +5 more
europepmc   +1 more source

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

FEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav, Bogdan I. Florea, Sebastian Geibel   +2 more
wiley   +1 more source

Data-reflector: an agentic exploratory data analysis platform for researchers. [PDF]

JAMIA Open
Sabounchi M, Hazare N, Capone C, Jangda M, Oh W, Jayaraman P, Gupta S, Sawant A, Kuschner Z, Parchure P, Timsina P, Kaplan B, Vakil A, Kohli-Seth R, Kovatch P, Zebrowski A, Glicksberg B, Agrawal P, Darrow B, Stump L, Charney A, Nadkarni GN, Sakhuja A.   +22 more
europepmc   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

FEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge, Vivian Pogenberg, Alexander Baumgart, Bente Siebels, Hartmut Schlüter, Michael Hecht‐Bucher, Aymelt Itzen   +6 more
wiley   +1 more source

Federated Time-to-Event Data Analysis Using Piecewise Exponential Regression in DataSHIELD. [PDF]

Stat Med
Svennblad B, Delcoigne B, Burton P, Avraam D.   +3 more
europepmc   +1 more source

Chiral separation of chloroalkanes with the chromatographic column onboard Martian rovers

FEBS Letters, EarlyView.
Computer image of the Rosalind Franklin Rover of ESA's ExoMars mission. ExoMars is scheduled to land on planet Mars in Oxia Planum in 2029. This area represents an interesting spot to look for biosignatures. Investigations of ExoMars include measurement on molecular chirality. We show that chiral chloroalkanes, that have been identified on Mars, can be
Asma Merzougui, Agnes Banreti, Armelle L. Ernst, Guillaume Leseigneur, Uwe J. Meierhenrich   +4 more
wiley   +1 more source

A Postprocessing Software Tool for 1H and 31P MRI Data Analysis. [PDF]

Top Magn Reson Imaging
Kassey VB, Walle M, Egan J, Kassey DV, Yeritsyan D, Wu Y, Snyder BD, Rodriguez EK, Ackerman JL, Nazarian A.   +9 more
europepmc   +1 more source

Induced abortions in Ohio (Online); Annual induced abortions in Ohio; Abortions

Annual; Electronic coverage as of May 8, 2008: 2001-; Chiefly statistical tables and graphs.; Description based on: 2001; title from Home page (last updated 4/24/2006, viewed on May 8, 2008).; Latest issue consulted: 2006.; Vol.
Center for Public Health Data and Statistics (Ohio). Statistical Analysis Unit.
core  

Prospecting the protein design landscape

FEBS Letters, EarlyView.
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona, Katharina T. Stonig, Jens Meiler, Clara T. Schoeder, Monica L. Fernández‐Quintero   +4 more
wiley   +1 more source

L‐aspartate oxidase provides new insights into fumarate reduction in anaerobic darkness in Synechocystis sp. PCC6803

FEBS Letters, EarlyView.
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil, Jeffrey A. Hawkes, Cecilia Blikstad, Pia Lindberg   +3 more
wiley   +1 more source