Results 201 to 210 of about 13,588,304 (249)

Low birth weight among neonates in rural areas of Indonesia: A secondary data analysis. [PDF]

Belitung Nurs J
Nelwati N, Malini H, Efendi F, Kuswanto H, Has EMM, Sampurna MTA.   +5 more
europepmc   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

Prevalence and occupational risk of hip osteoarthritis and rotator cuff lesions - claims data analysis. [PDF]

Int J Occup Med Environ Health
Hagenström K, Müller K, Klinger T, Augustin M, Nienhaus A.   +4 more
europepmc   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Prediction of cognitive impairment through speech data analysis: A comparative evaluation of deep learning models. [PDF]

PLoS One
Kim M, Choi H, Shim Y, Ryoo N, Jeong HT, Yun G, Lee H, Kim S, Youn YC.   +8 more
europepmc   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

REDAC: RNA-seq expression data analysis chatbot. [PDF]

Bioinform Adv
De Filippis GM, Sahu P, Ambrosio P, Picascia S, Lo Monte M, Agliarulo I, Di Paola S, Russo C, Tommasino C, Normanno N, Frezzetti D, Parashuraman S, Rinaldi AM, Russo F.   +13 more
europepmc   +1 more source

Direct Comparison of Three Postpartum Hemorrhage Risk Assessment Tools: A Retrospective Secondary Data Analysis. [PDF]

Obstet Gynecol Int
Modri S, Nagpal M, Brace M, Reddick YN, Weimer J, Sehdev H, Trout KK.   +6 more
europepmc   +1 more source

Guide to dynamic OCT data analysis. [PDF]

Biomed Opt Express
Heldt N, Monfort T, Morishita R, Schönherr R, Thouvenin O, El-Sadek IA, König P, Hüttmann G, Grieve K, Yasuno Y.   +9 more
europepmc   +1 more source

Characteristics of Human-Like Virtual Profiles in Relation to Audience Reach and Engagement on Instagram: Secondary Data Analysis. [PDF]

J Med Internet Res
Lebrecht AM, Tam W, Merlo O, Eisingerich AB.   +3 more
europepmc   +1 more source