Results 51 to 60 of about 249,220 (290)

Virtual reality for assessing stereopsis performance and eye characteristics in Post-COVID

open access: yesScientific Reports, 2023
In 2019, we faced a pandemic due to the coronavirus disease (COVID-19), with millions of confirmed cases and reported deaths. Even in recovered patients, symptoms can be persistent over weeks, termed Post-COVID. In addition to common symptoms of fatigue,
Wolfgang Mehringer   +9 more
doaj   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

open access: yesMolecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel   +6 more
wiley   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Automated long-term monitoring of stereotypical movement in polar bears under human care using machine learning

open access: yesEcological Informatics
The welfare of animals under human care is often assessed by observing behaviours indicative of stress or discomfort, such as stereotypical behaviour (SB), which often shows as repetitive, invariant pacing.
Matthias Zuerl   +9 more
doaj   +1 more source

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

open access: yesFEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini   +2 more
wiley   +1 more source

Modelling the Semantic Web using a Type System

open access: yes, 2015
We present an approach for modeling the Semantic Web as a type system. By using a type system, we can use symbolic representation for representing linked data.
Ciobanu G., Moten R.
core   +1 more source

Overview of molecular signatures of senescence and associated resources: pros and cons

open access: yesFEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas   +6 more
wiley   +1 more source

Review of Smart Meter Data Analytics: Applications, Methodologies, and Challenges

open access: yes, 2018
The widespread popularity of smart meters enables an immense amount of fine-grained electricity consumption data to be collected. Meanwhile, the deregulation of the power industry, particularly on the delivery side, has continuously been moving forward ...
Chen, Qixin   +3 more
core   +1 more source

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