Results 181 to 190 of about 21,724,191 (341)

Data on information sources, knowledge and practice on hepatitis B virus in southwest Nigeria. [PDF]

open access: yesData Brief, 2020
Adesina E   +5 more
europepmc   +1 more source

Past and Future Operations Concepts of NASA's Earth Science Data and Information System [PDF]

open access: yes
NASA committed to support the collection and distribution of Earth science data to study global change in the 1990's. A series of Earth science remote sensing satellites, the Earth Observing System (EOS), was to be the centerpiece.
Behnke, Jeanne   +2 more
core   +1 more source

Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine

open access: yesMolecular Oncology, EarlyView.
The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu   +18 more
wiley   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

open access: yesMolecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak   +8 more
wiley   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

open access: yesMolecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker   +16 more
wiley   +1 more source

Minimum information about a microarray experiment (MIAME)—toward standards for microarray data

open access: yesNature Genetics, 2001
A. Brazma   +23 more
semanticscholar   +1 more source

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