Results 91 to 100 of about 10,212,381 (290)
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Application of VISSR Atmospheric Sounder (VAS) data [PDF]
Sounding data which were derived from VAS radiance measurements and anticipated increased time and space resolution of the mesoscale environment are outlined.
Jedlovec, G. J.
core +1 more source
Time after time – circadian clocks through the lens of oscillator theory
FEBS Letters, EarlyView.Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
EntropyIn the absence of system-wide planning and coordination, emerging mobility services have been integrated into urban transportation systems as independent network layers.
Hongqing Bao +3 more
doaj +1 more source
Image data compression application to imaging spectrometers [PDF]
The potential of image data compression techniques to satisfy the anticipated requirements of imaging spectrometer missions is discussed.
Lee, J. J., Rice, R. F.
core +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
IEEE Journal of Selected Topics in Applied Earth Observations and Remote SensingThe segment anything model (SAM) enables zero-shot or interactive segmentation of visual content and has shown remarkable performance with natural images.
Tao Wu +4 more
doaj +1 more source
, 2018 Data-based solutions powered by artificial intelligence (AI), and especially its subdomain of machine learning, are a key driver of today’s fast-paced technological evolution. In the process industry, barriers for many organizations to apply this technology are missing know-how for conceptual planning as well as lack of economic feasibility studies ...
openaire +2 more sources