Results 111 to 120 of about 10,200,602 (244)

Geologic application of thermal inertia imaging using HCMM data [PDF]

Three test sites in the western US were selected to discriminate among surface geologic materials on the basis of their thermal properties as determined from HCMM data.
Abrams, M. J., Alley, R. E., Kahle, A. B., Levine, C. J., Schieldge, J. P.   +4 more
core   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

Crowding Perception Thresholds of Passengers in Urban Rail Transit: A Study of Differences in Spatiotemporal Dimensions

Journal of Advanced Transportation
This paper focuses on the differences in crowding perception among different types of passengers in trains, aiming to optimize passenger experience and improve the level of service of urban rail transit.
Xia Lu, Baohua Mao, Min Wang, Yixin Zhao, Peining Tian   +4 more
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Assessing nighttime artificial light pollution from the perspective of an unmanned aerial vehicle tilt

Geocarto International
Increasing artificial light at night (ALAN) impacts urban sustainability and contributes to light pollution. Nighttime satellites miss side ALAN, so drone-captured tilted images and measured illuminance are used to assess ALAN pollution within urban ...
Jiejie Wu, Liang Zhou, Deping Li, Daoquan Zhang, Tingting Jiang, Chengzhi Zong   +5 more
doaj   +1 more source

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Multispectral Remote Sensing Data Application in Modelling Non-Extensive Tsallis Thermodynamics for Mountain Forests in Northern Mongolia. [PDF]

Entropy (Basel), 2023
Sandlersky R, Petrzhik N, Jargalsaikhan T, Shironiya I.   +3 more
europepmc   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Variational Manifold Learning From Incomplete Data: Application to Multislice Dynamic MRI. [PDF]

IEEE Trans Med Imaging, 2022
Zou Q, Ahmed AH, Nagpal P, Priya S, Schulte RF, Jacob M.   +5 more
europepmc   +1 more source