Results 191 to 200 of about 4,379,512 (292)

Transitioning to digital transactional data capture in primary health care facilities: a case report from Ghana's Savannah Region. [PDF]

Mhealth
Abotsi E, Afenyadu G, Yentumi G, Nyuzaghl JA, Biritwum-Nyarko A, Ofosu AA, Tivura M, Ogunro A, Kowalski L, Eller L, Sullivan E.   +10 more
europepmc   +1 more source

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

FEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer, Angelique Kragl, Katrin Ziems, Juliane Glaubitz, Sophie Grammbauer, Susanne Hildebrandt, Mladen V. Tzvetkov, Gabriele Jedlitschky   +7 more
wiley   +1 more source

Efficiency of eSource Direct Data Capture in Investigator-Initiated Clinical Trials in Oncology. [PDF]

Ther Innov Regul Sci
Yaegashi H, Hayashi Y, Takeda M, Chiu SW, Nakayama H, Ito H, Takano A, Tsuboi M, Teramoto K, Suzuki H, Kato T, Yasui H, Nagamura F, Daigo Y, Yamaguchi T.   +14 more
europepmc   +1 more source

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source

Effectiveness of remote risk-based monitoring and potential benefits for combination with direct data capture. [PDF]

Trials
Yamada O, Chiu SW, Nakazawa T, Tsuda S, Yoshida M, Asano T, Kokubun T, Hashimoto K, Takata M, Ikeda S, Kawabe Y, Tamura Y, Yamaguchi T.   +12 more
europepmc   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

Technical article: Overview of hospital-based data capture systems that acquire continuous ECG and physiologic data. [PDF]

J Electrocardiol
Pelter MM, Prasad PA, Mortara DW, Badilini F.   +3 more
europepmc   +1 more source

Early‐life high‐fat diet exposure increases Achilles tendon stiffness and induces transcriptomic alterations

FEBS Open Bio, EarlyView.
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin, Ziyang Yuan, Wenli Jiang, Ai Guo   +3 more
wiley   +1 more source

Electronic data capture in resource-limited settings using the lightweight clinical data acquisition and recording system. [PDF]

Sci Rep
Vielhauer J, Mahajan UM, Adorjan K, Benesch C, Oehrle B, Beyer G, Sirtl S, Johlke AL, Allgeier J, Pernpruner A, Erber J, Shamsrizi P, Schulz C, Albashiti F, Hinske LC, Mayerle J, Stubbe HC.   +16 more
europepmc   +1 more source