Results 41 to 50 of about 4,379,512 (292)

Personalized Selumetinib Dosing in Pediatric Neurofibromatosis Type 1: Insights From a Pilot Therapeutic Drug Monitoring Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate selumetinib exposure using therapeutic drug monitoring (TDM) in pediatric patients with neurofibromatosis type 1 (NF1) and plexiform neurofibromas (PN), assess interpatient pharmacokinetic variability, and explore the relationship between drug exposure, clinical response, and adverse effects.
Janka Kovács, Zoltán Köllő, Balázs Gellért Karvaly, Mahmoud Obeidat, Rita Nagy, Péter Hegyi, Brigitta Teutsch, Eszter Tuboly, Miklós Garami   +8 more
wiley   +1 more source

Fine mapping chromatin contacts in capture Hi-C data

BMC Genomics, 2019
Background Hi-C and capture Hi-C (CHi-C) are used to map physical contacts between chromatin regions in cell nuclei using high-throughput sequencing.
Christiaan Q Eijsbouts, Oliver S Burren, Paul J Newcombe, Chris Wallace   +3 more
doaj   +1 more source

Capturing critical data elements in Juvenile Idiopathic Arthritis: initiatives to improve data capture

Pediatric Rheumatology Online Journal, 2022
Background Documentation of critical data elements is a focus of the Pediatric Rheumatology Care and Outcomes Improvement Network to aid in clinical care and research for patients with juvenile idiopathic arthritis.
Meghan E. Ryan, Andrew Warmin, Bryce A. Binstadt, Colleen K. Correll, Emily Hause, Patricia Hobday, Alison Lerman, Shawn A. Mahmud, Mona M. Riskalla, Zachary Shaheen, Richard K. Vehe, Danielle R. Bullock, the Pediatric Rheumatology Care, Outcomes Improvement Network   +13 more
doaj   +1 more source

CARRT—Motion Capture Data for Robotic Human Upper Body Model

Sensors, 2023
In recent years, researchers have focused on analyzing humans’ daily living activities to study various performance metrics that humans subconsciously optimize while performing a particular task.
Urvish Trivedi, Redwan Alqasemi, Rajiv Dubey   +2 more
doaj   +1 more source

Adherence to Protocol Recommendations for Children With Wilms Tumour in Two Consecutive Studies in the United Kingdom and Ireland—Does Variation Matter?

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background and Aims Wilms tumour (WT) has excellent event‐free and overall survival (OS). However, small differences exist between countries participating in the same international study. This led us to examine variation in adherence to protocol recommendations as a potential contributing factor.
Suzanne Tugnait, R. Al‐Saadi, A. Lopez‐Cortes, K. Dzhuma, M. Oostveen, J. Brok, S. Irtan, M. Weeks, J. Bate, S. Baker, R. Williams, M. Powis, D. Saunders, O. Olsen, T. Watson, S. Shelmerdine, S. Vaidya, L. Howell, C. Duncan, G. M. Vujanic, C. Stiller, G. P. Balchin, T. Chowdhury, K. Pritchard‐Jones   +23 more
wiley   +1 more source

How useful are data-driven methods for building-level greywater treatment from a process engineering perspective?

Water Research X
Data-driven methods are increasingly explored in various fields, demonstrating their potential. Compared with reviewing case-specific applications, this article critically assesses the usefulness of data-driven methods application from a process ...
Siyuan Wang, Mariane Y. Schneider, Eveline I.P. Volcke, Di Wu   +3 more
doaj   +1 more source

Brain-CODE: A Secure Neuroinformatics Platform for Management, Federation, Sharing and Analysis of Multi-Dimensional Neuroscience Data

Frontiers in Neuroinformatics, 2018
Historically, research databases have existed in isolation with no practical avenue for sharing or pooling medical data into high dimensional datasets that can be efficiently compared across databases.
Anthony L. Vaccarino, Anthony L. Vaccarino, Moyez Dharsee, Stephen Strother, Stephen Strother, Don Aldridge, Stephen R. Arnott, Stephen R. Arnott, Brendan Behan, Costas Dafnas, Fan Dong, Fan Dong, Kenneth Edgecombe, Rachad El-Badrawi, Khaled El-Emam, Tom Gee, Tom Gee, Susan G. Evans, Mojib Javadi, Francis Jeanson, Shannon Lefaivre, Kristen Lutz, F. Chris MacPhee, Jordan Mikkelsen, Tom Mikkelsen, Nicholas Mirotchnick, Tanya Schmah, Christa M. Studzinski, Donald T. Stuss, Donald T. Stuss, Donald T. Stuss, Elizabeth Theriault, Kenneth R. Evans   +32 more
doaj   +1 more source

Evaluating the Utility of Paired Tumor and Germline Targeted DNA Sequencing for Pediatric Oncology Patients: A Single Institution Report

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate the diagnostic yield and utility of universal paired tumor–normal multigene panel sequencing in newly diagnosed pediatric solid and central nervous system (CNS) tumor patients and to compare the detection of germline pathogenic/likely pathogenic variants (PV/LPVs) against established clinical referral criteria for cancer ...
Natalie Waligorski, Rebecca Ronsley, Shannon M. Stasi, Jeffrey Stevens, Erin R. Rudzinski, Christina M. Lockwood, Sarah E. S. Leary, Bonnie L. Cole, Michelle A. Ting, Vera Paulson   +9 more
wiley   +1 more source

Video-Based Human Motion Capture Data Retrieval via MotionSet Network

IEEE Access, 2020
Content-based human motion capture (MoCap) data retrieval facilitates reusing motion data that have already been captured and stored in a database. For a MoCap data retrieval system to get practically deployed, both high precision and natural interface ...
Tingxin Ren, Wei Li, Zifei Jiang, Xueqing Li, Yan Huang, Jingliang Peng   +5 more
doaj   +1 more source

Using visual encounter data to improve capture–recapture abundance estimates

Ecosphere, 2021
Capture–recapture studies are widely used in ecology to estimate population sizes and demographic rates. In some capture–recapture studies, individuals may be visually encountered but not identified.
Maxwell B. Joseph, Roland A. Knapp
doaj   +1 more source