Results 161 to 170 of about 11,273,440 (292)

Research on energy efficiency optimization of data centers based on DC-Bi-LSTM network integration algorithm

open access: yesDianxin kexue
With the popularization of cloud computing and big data technology, the energy consumption problem of data centers has become increasingly prominent. How to achieve energy efficiency optimization through intelligent algorithms has become a key issue in ...
OUYANG Shujia   +4 more
doaj  

[Research Data Center on Health - Vision for Further Development from the Research Perspective]. [PDF]

open access: yesGesundheitswesen, 2023
March S   +12 more
europepmc   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

Interpretability Study on the Fault Diagnosis Model of the Heat pipe/ Vapor Compression Composite Air Conditioning System

open access: yesZhileng xuebao
Applying data-driven fault diagnosis models to data center air conditioning systems can significantly improve operational reliability. However, such models often lack diagnostic interpretability, limiting their application.
ZHANG Yiqi   +5 more
doaj  

Home - About - Disclaimer - Privacy