Results 61 to 70 of about 511,690 (285)
Pediatric Blood &Cancer, EarlyView.ABSTRACT Objective To evaluate selumetinib exposure using therapeutic drug monitoring (TDM) in pediatric patients with neurofibromatosis type 1 (NF1) and plexiform neurofibromas (PN), assess interpatient pharmacokinetic variability, and explore the relationship between drug exposure, clinical response, and adverse effects.
Janka Kovács +8 more
wiley +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background and Aims Wilms tumour (WT) has excellent event‐free and overall survival (OS). However, small differences exist between countries participating in the same international study. This led us to examine variation in adherence to protocol recommendations as a potential contributing factor.
Suzanne Tugnait +23 more
wiley +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Arteriovenous malformations (AVMs) are rare, high‐flow, vascular anomalies that can occur either sporadically or as part of a genetic syndrome. AVMs can progress with serious morbidity and even mortality if left unchecked. Sirolimus is an mTOR inhibitor that is effective in low‐flow vascular malformations; however, its role in AVMs is unclear.
Will Swansson +3 more
wiley +1 more source
Weakly-Supervised Multilingual Medical NER for Symptom Extraction for Low-Resource Languages
Applied SciencesPatient-reported health data, especially patient-reported outcomes measures, are vital for improving clinical care but are often limited by memory bias, cognitive load, and inflexible questionnaires.
Rigon Sallauka +3 more
doaj +1 more source
Corrosion prediction for bulk carrier via data fusion of survey and experimental measurements
Materials & Design, 2021 Accurate corrosion predictions are vital to safe and optimised designs of marine assets. Traditional approaches, including those used to develop rule requirements, seek to use empirical regressions to model corrosion, but most are solely time-dependent ...
Z. Wang, A.J. Sobey, Y. Wang
doaj +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Objective To evaluate the diagnostic yield and utility of universal paired tumor–normal multigene panel sequencing in newly diagnosed pediatric solid and central nervous system (CNS) tumor patients and to compare the detection of germline pathogenic/likely pathogenic variants (PV/LPVs) against established clinical referral criteria for cancer ...
Natalie Waligorski +9 more
wiley +1 more source
Numerical simulation, clustering, and prediction of multicomponent polymer precipitation
Data-Centric Engineering, 2020 Multicomponent polymer systems are of interest in organic photovoltaic and drug delivery applications, among others where diverse morphologies influence performance.
Pavan Inguva +4 more
doaj +1 more source
First-Class Functions for First-Order Database Engines [PDF]
, 2013 We describe Query Defunctionalization which enables off-the-shelf first-order database engines to process queries over first-class functions. Support for first-class functions is characterized by the ability to treat functions like regular data items ...
Grust, Torsten, Ulrich, Alexander
core
Data-centric biology: a philosophical study [PDF]
New Genetics and Society, 2017 With the rise of “big data,” we are seeing an increase in data-centrism across many fields of human endeavor, including the life sciences. How should we make sense of these developments?
openaire +3 more sources