Results 211 to 220 of about 6,032,510 (313)

Usefulness of lung sound data collection using Skeeper SM-300® device: A pilot study. [PDF]

PLoS One
Choi SI, Jeong Y, Jung WJ, Kim BK, Lee SY, Lee J, Kim J, Cho WY, Chang H, An H, Park S, Lee EJ.   +11 more
europepmc   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Providing Psychological Therapy Support and Improving Postdischarge Data Collection: Preliminary Evaluation of the "Paddle" App. [PDF]

JMIR Hum Factors
Thew GR, Lee M, Wolsey I, Giles F, Hayden E, Jell G, Peacock J, Pimm J, Ryder J, Salvadori A, Clark DM.   +10 more
europepmc   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source

Errors in Data Collection and Calculations.

JAMA Surg
europepmc   +1 more source

Recommendations for biomarker data collection in clinical trials by longevity biotechnology companies. [PDF]

NPJ Aging
Herzog CMS, Poganik JR, Boekstein N, Fortney K, Peyer JG, Mellon J, Starr R, Barzilai N, Moqri M.   +8 more
europepmc   +1 more source

AscF in the mycobacterial CIII–CIV supercomplex lacks metal and nucleotide binding but links malate oxidation to respiration

FEBS Letters, EarlyView.
The mycobacterial CIII‐CIV respiratory supercomplex is an obligate assembly, encompassing several subunits of unknown functions. We have characterized the intracellular subunit AscF, and show that it is unlikely to be a sensor for metals or nucleotides, but is required for growth on nonfermentable energy sources, and likely works as an adapter for ...
Eni Rile, Riccardo Diamanti, Daniel Lundin, Soni Sharma, Robin Lissner, Coenraad P. Kuil, Martin Högbom, Dirk Bald, Dan Sjöstrand   +8 more
wiley   +1 more source

Potential for Bias in Social Needs Data Collection and Screening Activities in Health Care Settings.

JAMA Health Forum
Vest JR, Harle CA, McNamee C, Hammer NC, Gregory ME.   +4 more
europepmc   +1 more source