Results 241 to 250 of about 6,032,510 (313)

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Falls Among Residents Living in Care Homes Using Real-Time Data Collection: A Large UK Case-Control Study. [PDF]

Health Sci Rep
Gertner J, Dvir O, Shifrin N, Wolfson P, Moskovitch R, Lovat LB.   +5 more
europepmc   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source

Conversational, Longitudinal, Ecological Assessment (CLEA): Exploring a new AI-driven method for qualitative data collection in a behavioural health context. [PDF]

PLOS Digit Health
Downes S, Krys T, O'Hara K, Western M, Thompson L, Brigden A.   +5 more
europepmc   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Sports injury surveillance practices and data collection methods in university student athletes: A systematic review. [PDF]

J Sport Health Sci
Schippers RC, Andrews B, Meeusen R, Verhagen E, Verschueren J, Tassignon B, Leach L.   +6 more
europepmc   +1 more source

Accelerating real-world data collection using large language models in rare neoplasms: a bone sarcoma example. [PDF]

ESMO Real World Data Digit Oncol
Teterycz P, Rynkun S, Szostakowski B, Wągrodzki M, Rutkowski P, Rosińska M.   +5 more
europepmc   +1 more source

Opportunities for Epidemiological Data Collection in Dental Practices: A Thematic Analysis of Dutch Dentists' Views. [PDF]

Int Dent J
den Boer JCL, Schulpen M, van Meijeren-van Lunteren AW, van Spreuwel PCJM, Everaars B, Bruers JJM.   +5 more
europepmc   +1 more source

Rapid Epidemiological Data Collection on Social Media for COVID-19: Comparative Study Between Online Surveys and Conventional Cohorts. [PDF]

J Med Internet Res
Mortaga M, Nunner H, Paltra S, Stellbrink L, Friedel J, Harries M, Krepel J, Lange B, MuSPAD Study Group, Priesemann V, Calero Valdez A.   +10 more
europepmc   +1 more source