Results 61 to 70 of about 3,772,561 (311)

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

The anti‐CRISPR protein AcrIE8.1 inhibits the type I‐E CRISPR‐Cas system by directly binding to the Cascade subunit Cas11

FEBS Letters, EarlyView.
In this study, we present the structure of AcrIE8.1, a previously uncharacterized anti‐CRISPR protein that inhibits the type I‐E CRISPR‐Cas system. Through a combination of structural and biochemical analyses, we demonstrate that AcrIE8.1 directly binds to the Cas11 subunit of the Cascade complex to inhibit the CRISPR‐Cas system.
Young Woo Kang, Hyun Ho Park
wiley   +1 more source

Data Collection and Leakage [PDF]

, 2010
Every year millions of digital records containing personally identifiable information are exposed. When are malicious hackers to blame, and when is it organizational malfeasance? Which kinds of organizations—private firms, government agencies, or educational institutions—loose the most data?
Howard, Philip, Erickson, Kris
openaire   +1 more source

An intracellular transporter mitigates the CO2‐induced decline in iron content in Arabidopsis shoots

FEBS Letters, EarlyView.
This study identifies a gene encoding a transmembrane protein, MIC, which contributes to the reduction of shoot Fe content observed in plants under elevated CO2. MIC is a putative Fe transporter localized to the Golgi and endosomal compartments. Its post‐translational regulation in roots may represent a potential target for improving plant nutrition ...
Timothy Mozzanino, Meijie Li, Cécile Fizames, Mattia Adamo, Laurence Lejay, Christian Dubos, Matthieu Platre, Antoine Martin   +7 more
wiley   +1 more source

Global Roadkill Data: a dataset on terrestrial vertebrate mortality caused by collision with vehicles

Scientific Data
Roadkill is widely recognized as one of the primary negative effects of roads on many wildlife species and also has socioeconomic impacts when they result in accidents.
Clara Grilo, Tomé Neves, Jennifer Bates, Aliza le Roux, Pablo Medrano-Vizcaíno, Mattia Quaranta, Inês Silva, Kylie Soanes, Yun Wang, Data Collection Consortium   +9 more
doaj   +1 more source

Handling missing data in research

Perspectives in Clinical Research
Missing data are an inevitable part of research and lead to a decrease in the size of the analyzable population, and biased and imprecise estimates. In this article, we discuss the types of missing data, methods to handle missing data and suggest ways in
Priya Ranganathan, Sally Hunsberger
doaj   +1 more source

A Cre‐dependent lentiviral vector for neuron subtype‐specific expression of large proteins

FEBS Letters, EarlyView.
We designed a versatile and modular lentivector comprising a Cre‐dependent switch and self‐cleaving 2A peptide and tested it for co‐expression of GFP and a 2.8 kb gene of interest (GOI) in mouse cortical parvalbumin (PV+) interneurons and midbrain dopamine (TH+) neurons.
Weixuan Xue, Sandrine Picaud, Régine Hepp, Stéphanie Pons, Uwe Maskos, Bertrand Lambolez, Ludovic Tricoire   +6 more
wiley   +1 more source

Academic Performance and Satisfaction of Student-Directed Learning in Online Education Among Multidisciplinary Undergraduate Students: A Retrospective Comparative Study

SAGE Open Nursing
Introduction The outcomes of student-directed learning (SDL) compared to teacher-directed learning (TDL) in online education is yet to be established.
Basma Al Yazeedi PhD, Zeinab Al Azri PhD, Lina Shakman MSN, Safiya Al Shidhani MED, Maryam Al Kharusi BSc   +4 more
doaj   +1 more source

Risk factors for adverse outcomes at various phases of endoscopic ultrasound‐guided treatment of pancreatic fluid collections: Data from a multi‐institutional consortium

, 2023
Tomotaka Saito, Shunsuke Omoto, Mamoru Takenaka, Masahiro Tsujimae, Atsuhiro Masuda, Tatsuya Sato, Tsuyoshi Hamada, Shogo Ota, Hideyuki Shiomi, Sho Takahashi, Toshio Fujisawa, Keito Nakagawa, Saburo Matsubara, Shinya Uemura, Takuji Iwashita, Kensaku Yoshida, Akinori Maruta, Mitsuru Okuno, Keisuke Iwata, Nobuhiko Hayashi, Tsuyoshi Mukai, Hiroyuki Isayama, Ichiro Yasuda, Yousuke Nakai   +23 more
openalex   +2 more sources

Rural Water Collection Patterns: Combining Smart Meter Data with User Experiences in Tanzania [PDF]

, 2020
Will Ingram, Fayyaz Ali Memon
openalex   +1 more source