The therapeutic efficacy of lipid nanoparticle(LNP)‐based drugs depends on endosomal escape. However, few methods are available for quantifying the efficiency of endosomal escape in vivo. Herein, a novel method for quantifying the endosomal escape efficiency index using magnetic resonance imaging is introduced.
Somin Lee +5 more
wiley +1 more source
Chemical Composition and Backbone Modifications Define Deformability of Nucleic Acid Nanoparticles. [PDF]
Pandey L +7 more
europepmc +1 more source
Biomimetic Scaffolds with Dual Gradients of Biological Effectors for Tendon‐to‐Bone Repair
The authors have developed a biomimetic scaffold with dual gradients through a diffusion‐driven method. The scaffold features funnel‐shaped microchannels for cell infiltration, while the dual gradients synergetically induce the graded differentiation of mesenchymal stem cells into osteoblasts, chondrocytes, and tenocytes, allowing for a seamless ...
Min Hao +3 more
wiley +1 more source
Preparation, Performance Research and Field Application Practice of Temperature-Sensitive Lost Circulation Material for Shale Oil Wells. [PDF]
Zhang W +9 more
europepmc +1 more source
A surface cover change detection method based on the Australian Geoscience Data Cube
P. Tan +5 more
openalex +1 more source
Partitioned Cube: Condensed Storage and Fast Access for Data Cube
openaire +2 more sources
Microphysiological Systems of Lymphatics and Immune Organs
This review surveys recent progress in engineering lymphatic microenvironments and immune organoids within microphysiological systems, emphasizing innovative strategies to recreate the biochemical and biophysical complexity of native lymphatic tissues.
Ishita Jain +2 more
wiley +1 more source
In-Orbit Optimal Safe Formation Control for Surrounding an Unknown Huge Target with Specific Structure by Using Relative Sensors Only. [PDF]
Wei B, Li C, Dang Z, Yue X.
europepmc +1 more source
Plug‐and‐Play Centrifuge‐Only Device for Rapid Sepsis Diagnosis
A fully automated, centrifuge‐only device can isolate and concentrate bacteria from blood for rapid sepsis diagnosis. The device enables >3×$>3\times$ bacterial enrichment and removes >$>$99.9% of blood cells. The device supports direct downstream analysis via subculturing, MALDI‐TOF, and microfluidic detection of bacteria.
Mohammad Osaid +5 more
wiley +1 more source

