Results 241 to 250 of about 70,218 (315)

Hyperandrogenemia Induces Trophoblast Ferroptosis and Early Pregnancy Loss in Patients With PCOS via CMA‐Dependent FTH1 Degradation

Advanced Science, EarlyView.
In PCOS patients with hyperandrogenemia, decreased ferritin heavy chain 1 (FTH1) causes Fe2⁺ overload and ferroptosis in trophoblasts. Androgens induce FTH1 protein degradation via AR‐LAMP2A‐mediated chaperone‐mediated autophagy pathway, leading to placental development disruption and early pregnancy loss. Metformin mitigates androgen‐induced placental
Hanjing Zhou, Weijie Yang, Na Liu, Qing Liu, Jiamin Jin, Chenqiong Zhao, Xiaoying Jin, Miao Gui, Haiyan Zhu, Songying Zhang, Yinli Zhang   +10 more
wiley   +1 more source

A privacy-protecting eggplant disease detection framework based on the YOLOv11n-12D model. [PDF]

Front Plant Sci
Han J, Wu Z, Ding Y, Guo Y, Fu R.
europepmc   +1 more source

Tailoring Vascular‐Immune Homeostasis via Manganese‐DNA Complex‐Armed Immunogenic Extracellular Vesicles for Pancreatic Cancer Immunotherapy

Advanced Science, EarlyView.
This study demonstrates that Mn2⁺–tumor DNA complexes encapsulated in dendritic cell (DC)– derived immunogenic extracellular vesicles (EVDC@Mn‐DNA) act as a DC‐specific cGAS– STING activator. EVDC@Mn‐DNA treatment enhances intratumoral DC activation, improves tumor vascular function, promotes CD8⁺ T cell activity, and suppresses pancreatic tumor growth,
Xue Jiang, Lihuan Shang, Xiaochun Chen, Xiangzhan Kong, Xiaojuan Wang, Linjia Jiang, Huiying Zhao, Yafeng Zhu, Cheng Huang, Shiyi Deng, Rui Zhang, Minghui Wang, Haoming Lin, Ping‐Pui Wong   +13 more
wiley   +1 more source

From pixels to pores: 3D-(im)printed hierarchically porous polymer monoliths. [PDF]

iScience
Keitel B, Schimana S, Huber A, Yoshida Y, Shioji H, Furushima Y, Sevinis Ozbulut EB, Ohkawa T, Yoshimoto S, Kubo T, Hosomi H, Kato T, Uehara F, Futamura H, Nakanishi K, Noda A, Yamamoto T, Mizaikoff B, Dinc M.   +18 more
europepmc   +1 more source

USP9X as a Candidate Mediator of Prenatal Aspirin‐Induced Ovarian Reserve Reduction in Offspring Mice

Advanced Science, EarlyView.
This study suggests that prenatal aspirin exposure is associated with reduced ovarian reserve in offspring, associated with HDAC1‐linked epigenetic downregulation of Usp9x as a candidate mechanism. These preclinical findings provide new insights into fetal‐origin ovarian disorders and contribute to the evidence base concerning aspirin's gestational ...
Yating Li, Caiyun Ge, Wai Yen Yim, Hui Feng, Tiancheng Wu, Lu Chen, Qiaohua Xiong, Shumin Pan, Mei Wang, Huijun Chen, Yuanzhen Zhang, Hui Wang   +11 more
wiley   +1 more source

III-Nitrides empower miniaturized spectral imager in ultraviolet. [PDF]

Light Sci Appl
Zhao Y, Li T, Ooi B.
europepmc   +1 more source

Data Cube Materialization with MR Cube and CM Sketch Approach

International Journal of Science and Research (IJSR), 2015
openaire   +1 more source

Data Cube API - Release I

D42 Data Cube API This deliverable resulting from tasks T42 and T43 will include the tools to discover explore access FAIR Data Cubes Two releases are planned to provide the project partners with an incremental set of functionalities to handle FAIR Data ...
openaire   +1 more source

C2A-DC: A context-aware adaptive data cube framework for environmental monitoring and climate change crisis management

Αναστάσιος Τέμενος, Nikos Temenos, Ioannis N. Tzortzis, Ioannis Rallis, Anastasios Doulamis, Nikolaos Doulamis   +5 more
openalex   +1 more source

Top‐Down Fabricated Wood‐Derived Pressure and Strain Sensors: A Review

Advanced Science, EarlyView.
This review focuses on wood‐derived pressure/strain sensors fabricated via top‐down strategies. It analyzes wood's structural composition, examines processing techniques, discusses sensor types and sensing mechanisms, and reviews existing research. The article concludes with future directions for enhancing performance and scalability.
Yi Ren, Fuyao Liu, Yanan Zhong, Shengbo Ge, Zhipeng Shi, Siling Lin, Hongli Song, Yingying Zhang, Wei Fan   +8 more
wiley   +1 more source