Results 21 to 30 of about 157,157 (179)

Possible role of human ribonuclease dicer in the regulation of R loops

FEBS Open Bio, EarlyView.
R loops play an important role in regulating key cellular processes such as replication, transcription, centromere stabilization, or control of telomere length. However, the unscheduled accumulation of R loops can cause many diseases, including cancer, and neurodegenerative or inflammatory disorders. Interestingly, accumulating data indicate a possible
Klaudia Wojcik, Paulina Krzeminska, Anna Kurzynska‐Kokorniak   +2 more
wiley   +1 more source

Knockout of the mitoribosome rescue factors Ict1 or Mtrfr is viable in zebrafish but not mice: compensatory mechanisms underlying each factor's loss

FEBS Open Bio, EarlyView.
Mitochondria contain two mitoribosome rescue factors, ICT1 and MTRFR (C12orf65). ICT1 also functions as a mitoribosomal protein in mice and humans, and its loss is lethal. Although Mtrfr knockout mice could not be generated, knockout zebrafish lines for ict1 and mtrfr were established.
Nobukazu Nameki, Chika Tomisawa, Soichiro Hoshino, Hidehiko Shimizu, Masashi Abe, Sho Arai, Kanako Kuwasako, Naoki Asakawa, Yusuke Inoue, Takuro Horii, Izuho Hatada, Masakatsu Watanabe   +11 more
wiley   +1 more source

Profiling the effect of low frequency mechanical vibration on the metabolic and oxidative stress responses of A431 carcinoma

FEBS Open Bio, EarlyView.
20 Hz mechanical vibration induced A431 cancer cells' apoptosis without such effect on other healthy cell lines of L929 and C2C12. Lowered glucose consumption is observed specifically in A431. The expressions of ROS, HMGB1, and HSP1 levels initially increase and subsequently decrease in the cancer cell line, as opposed to L929 and C2C12, which ...
Wresti L. Anggayasti, Chikahiro Imashiro, Takashi Morikura, Shogo Miyata, Akira Funahashi, Kenjiro Takemura   +5 more
wiley   +1 more source

Interactive Visualization of the Largest Radioastronomy Cubes

, 2010
3D visualization is an important data analysis and knowledge discovery tool, however, interactive visualization of large 3D astronomical datasets poses a challenge for many existing data visualization packages.
A.H. Hassan, Barnes, Becciani, Beeson, C.J. Fluke, D.G. Barnes, Drebin, Goel, Graham, Hamada, Lacroute, Levoy, Li, Lombeyda, McClure-Griffiths, Oosterloo, Pence, Sabella, Samet, Schive, Thibault, Wayth   +21 more
core   +1 more source

A review of artificial intelligence in brachytherapy

Journal of Applied Clinical Medical Physics, EarlyView.
Abstract Artificial intelligence (AI) has the potential to revolutionize brachytherapy's clinical workflow. This review comprehensively examines the application of AI, focusing on machine learning and deep learning, in various aspects of brachytherapy.
Jingchu Chen, Richard L. J. Qiu, Tonghe Wang, Shadab Momin, Xiaofeng Yang   +4 more
wiley   +1 more source

Stereotactic radiosurgery for multiple small brain metastases using gamma knife versus single‐isocenter VMAT: Normal brain dose based on lesion number and size

Journal of Applied Clinical Medical Physics, EarlyView.
Abstract Purpose The study evaluates rapid linear accelerator (Linac) single isocenter stereotactic radiosurgery (SRS) with Hyperarc for large target numbers. We compared to Gamma Knife (GK), which suffers from long treatment times and investigated causes of differences. Methods Linac SRS and GK treatment plans for patients receiving 18 Gy to the gross
Abram Abdou, Timoteo Almeida, Elizabeth Bossart, Irene Monterroso, Eric A. Mellon   +4 more
wiley   +1 more source

A Cloud Tracking Tool for Planetary Orbiter Images [PDF]

, 2005
During their operations phase, planetary missions continuously produce a wealth of data that tend to overwhelm research teams. Spectral imagers, in particular, produce data cubes in which the wavelength dimension adds to the two spatial dimensions ...
Berry, David L., Gil, Rute, Luz, David, Roos-Serote, Maarten   +3 more
core  

NGC 7097: the AGN and its mirror, revealed by PCA Tomography

, 2011
Three-dimensional (3D) spectroscopy techniques are becoming more and more popular, producing an increasing number of large data cubes. The challenge of extracting information from these cubes requires the development of new techniques for data processing
Menezes, R. B., Ricci, T. V., Steiner, J. E.   +2 more
core   +1 more source

Effects of Staggered Array of Cubical Obstacles on Near- Ground Wind Environment and Air Quality [PDF]

, 2019
Deterioration of natural ventilation in outdoor environments due to rapid urbanisation has raised the issues pertaining to pedestrians’ thermal comforts and pollutant exposures. There are substantial interests in the recent years to get an insight on how
Abidin, Ummikalsom, Badar Sharif, Asyraf Sharif, Che Sidik, Nor Azwadi, Hanipah, M. H., Mohd Zawawi, Fazila, Muhammad Yazid, Muhammad Noor Afiq Witri   +5 more
core   +1 more source

Geometric and dosimetric evaluation of a commercial AI auto‐contouring tool on multiple anatomical sites in CT scans

Journal of Applied Clinical Medical Physics, EarlyView.
Abstract Current radiotherapy practices rely on manual contouring of CT scans, which is time‐consuming, prone to variability, and requires highly trained experts. There is a need for more efficient and consistent contouring methods. This study evaluated the performance of the Varian Ethos AI auto‐contouring tool to assess its potential integration into
Robert N. Finnegan, Alexandra Quinn, Patrick Horsley, Joseph Chan, Maegan Stewart, Regina Bromley, Jeremy Booth   +6 more
wiley   +1 more source