Results 121 to 130 of about 4,521,731 (325)

Isoparametric 3-D Finite Element Mesh Generation Using Interactive Computer Graphics [PDF]

, 1985
An isoparametric 3-D finite element mesh generator was developed with direct interface to an interactive geometric modeler program called POLYGON. POLYGON defines the model geometry in terms of boundaries and mesh regions for the mesh generator. The mesh
Kayrak, C., Ozsoy, T.
core   +1 more source

Functional role and folding properties of the glucan‐binding domain of oral bacterial glucansucrase

FEBS Letters, EarlyView.
The role of the glucan‐binding domain in Streptococcus sobrinus glucansucrase was examined, focusing on its impact on enzymatic activity, dextran binding, and structural stability of deletion mutants and a circularly permuted protein. Our research revealed that glucosyl transfer efficiency is linked to cooperative interdomain folding.
Hideyuki Komatsu, Takayuki Sadakane, Yudai Murata, Junichi Taira, Hiroshi Sakamoto, Takao Kodama   +5 more
wiley   +1 more source

MET variants with activating N‐lobe mutations identified in hereditary papillary renal cell carcinomas still require ligand stimulation

Molecular Oncology, EarlyView.
MET variants in the N‐lobe of the kinase domain, found in hereditary papillary renal cell carcinoma, require ligand stimulation to promote cell transformation, in contrast to other RTK variants. This suggests that HGF expression in the microenvironment is important for tumor growth in such patients. Their sensitivity to MET inhibitors opens the way for
Célia Guérin, Audrey Vinchent, Marie Fernandes, Isabelle Damour, Agathe Laratte, Rémi Tellier, Gabriella O. Estevam, Jean‐Pascal Meneboo, Céline Villenet, Clotilde Descarpentries, James S. Fraser, Martin Figeac, Alexis B. Cortot, Etienne Rouleau, David Tulasne   +14 more
wiley   +1 more source

Journey of a Data Element to Data Interoperability and Reuse

Poor health data interoperability has been an issue for more than 25 years. With the emergence of data-hungry AI solutions, the need for interoperable and reusable health data is growing. This paper presents a prototype virtual assistant, developed and tested as part of the AIDAVA Horizon Europe project, that creates an interoperable and reusable ...
Isabelle de Zegher, Remzi Celebi
openaire   +3 more sources

Ni-cd Battery Life Expectancy in Geosynchronous Orbit [PDF]

, 1984
The feasibility of using nickel cadmium batteries as an alternate if flight qualified NiH2 batteries are not available is explored. Battery life expectancy data being a key element of power system design, an attempt is made to review the literature, life
Broderick, R. J.
core   +1 more source

Response to neoadjuvant chemotherapy in early breast cancers is associated with epithelial–mesenchymal transition and tumor‐infiltrating lymphocytes

Molecular Oncology, EarlyView.
Epithelial–mesenchymal transition (EMT) and tumor‐infiltrating lymphocytes (TILs) are associated with early breast cancer response to neoadjuvant chemotherapy (NAC). This study evaluated EMT and TIL shifts, with immunofluorescence and RNA sequencing, at diagnosis and in residual tumors as potential biomarkers associated with treatment response.
Françoise Derouane, Jérôme Ambroise, Cédric van Marcke, Mieke Van Bockstal, Martine Berlière, Christine Galant, Hélène Dano, Médina Lougué, Elena Benidovskaya, Guy Jerusalem, Vincent Bours, Claire Josse, Jérôme Thiry, Aurélie Daumerie, Caroline Bouzin, Cyril Corbet, François P. Duhoux   +16 more
wiley   +1 more source

The Time-Dependent Schrödinger Equation, Riccati Equation, and Airy Functions

Physics
We construct the Green functions (or Feynman’s propagators) for the Schrödinger equations of the form iψt+14ψxx±tx2ψ=0 (for the wave function ψ and its time (t) and x-space derivatives) in terms of Airy functions and solve the Cauchy initial value ...
Nathan A. Lanfear, Sergei K. Suslov
doaj   +1 more source

Electronic file of geochemical trace-element data for stream sediment samples collected in the Circle mining district, 1983 [PDF]

, 1994
M. A. Wiltse, P.A. Metz, M. S. Robinson, D. S. Pinney   +3 more
openalex   +1 more source

Peripheral blood proteome biomarkers distinguish immunosuppressive features of cancer progression

Molecular Oncology, EarlyView.
Immune status significantly influences cancer progression. This study used plasma proteomics to analyze benign 67NR and malignant 4T1 breast tumor models at early and late tumor stages. Immune‐related proteins–osteopontin (Spp1), lactotransferrin (Ltf), calreticulin (Calr) and peroxiredoxin 2 (Prdx2)–were associated with systemic myeloid‐derived ...
Yeon Ji Park, Jae Won Oh, Hyewon Chung, Jung Won Kwon, Yi Rang Na, Kwang Pyo Kim, Seung Hyeok Seok   +6 more
wiley   +1 more source

Framework for Data Element Standardization

Advances in Classification Research Online, 1995
This paper describes a method for the definition of data elements in CASE (Computer-Assisted Systems/Software Engineering) systems, data element dictionaries, and data element repositories. The proposed method derives its power from its simplicity and its use of classification and knowledge representation techniques.
openaire   +2 more sources