Results 181 to 190 of about 4,882,254 (344)

Machine Learning-Based Tectonic Discrimination Using Basalt Element Geochemical Data: Insights into the Carboniferous–Permian Tectonic Regime of Western Tianshan Orogen [PDF]

Hengxu Li, Mengqi Gao, Xiaohui Ji, Zhaochong Zhang, Zhiguo Cheng, M. Santosh   +5 more
openalex   +1 more source

Finite Element Modeling of Atlantoaxial Joint with the Vertebral Artery Based on CT Data [PDF]

, 2016
Shaoyin Duan, Li Zhang, Changhua Lin, Hua Zhong   +3 more
openalex   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

Research category and future development trend of data elements circulation and security

Tongxin xuebao
Towards the trend of evolution from controlled data sharing in the information technology era to ubiquitous circulation of data elements in the data technology era, the difference between data sharing and data element circulation was analyzed, what kind ...
LI Fenghua, LI Hui, NIU Ben, QIU Weidong
doaj   +2 more sources

Cell density–dependent nuclear‐cytoplasmic shuttling of SETDB1 integrates with Hippo signaling to regulate YAP1‐mediated transcription

FEBS Letters, EarlyView.
At low cell density, SETDB1 and YAP1 accumulate in the nucleus. As cell density increases, the Hippo pathway is gradually activated, and SETDB1 is associated with increased YAP1 phosphorylation. At high cell density, phosphorylated YAP1 is sequestered in the cytoplasm, while SETDB1 becomes polyubiquitinated and degraded by the ubiquitin–proteasome ...
Jaemin Eom, Jaewoong Jang, Jung Sun Park, Yong‐Kook Kang   +3 more
wiley   +1 more source

How does the data element-driven industry affect corporate cash holdings? Evidence from Chinese listed companies. [PDF]

Heliyon
Xiang Y, Xu M.
europepmc   +1 more source

LA-ICP-MS Trace Element Data for Sulfide Minerals from Mid-Ocean Ridge Hydrothermal Vent Field

Fan, Lei, Holzheid, Astrid, Zoheir, Basem, Wang, Guozhi, Li, Chuanshun, Frische, Matthias, Shi, Xuefa   +6 more
openalex   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

Molecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero, Alejandro Belmonte‐Fernández, Mónica González‐Moreno, Laura Rodríguez‐Cordero, Begoña Pérez‐Valderrama, Joaquín Herrero‐Ruíz, Francisco Romero, Carmen Sáez, Miguel Á. Japón   +8 more
wiley   +1 more source

Clinical and biobehavioral phenotypic assessments and data harmonization for the RE-JOIN research consortium: Recommendations for common data element selection. [PDF]

Neurobiol Pain
Cruz-Almeida Y, Mehta B, Haelterman NA, Johnson AJ, Heiting C, Ernberg M, Orange D, Lotz M, Boccanfuso J, Smith SB, Pela M, Boline J, Otero M, Allen K, Perez D, Donnelly C, Almarza A, Olmer M, Balkhi H, Wagenaar J, Martone M, RE-JOIN Consortium Investigators.   +21 more
europepmc   +1 more source