Results 291 to 300 of about 1,093,487 (365)
Translating whole‐genome doubling into precision medicine in cancer
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley +1 more source
Towards optimized CT lung cancer screening scan protocols. [PDF]
Iball GR, Porter CA.
europepmc +1 more source
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley +1 more source
Primary malignant peripheral nerve sheath tumor of the liver: a case report and literature review. [PDF]
Hu X, Zhou L, Tian Y, Li X, Lu T.
europepmc +1 more source
Enhancing Document AI Data Generation Through Graph-Based Synthetic Layouts
Amit Agarwal +3 more
openalex +1 more source
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu +3 more
wiley +1 more source
GPRF-HPNet Physics-guided texture-aware fusion for real-world underwater image enhancement. [PDF]
Xu J +6 more
europepmc +1 more source
Nonlinear and intensity-dependent enhancement of sweetness perception as a function of redness: Behavioral and EEG evidence for visual-gustatory cross-modal integration. [PDF]
Sun Y +5 more
europepmc +1 more source

