Data exploration on the factors associated with cost overrun on social housing projects in Trinidad and Tobago. [PDF]
Chadee AA +4 more
europepmc +1 more source
AbstractThis chapter presents three unrelated tools that all assist a researcher with interpreting their results after their data is coded (or from the moment a substantial part of the data is coded). The first tool is the Explore Diagram. The Explore Diagram is a dynamic diagram that allows the researcher to virtually “walk around” through their data.
openaire +1 more source
Overview of molecular signatures of senescence and associated resources: pros and cons
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas +6 more
wiley +1 more source
Practical considerations for data exploration in quantitative cell biology.
Pylvänäinen JW, Grobe H, Jacquemet G.
europepmc +1 more source
Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity
Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz +9 more
wiley +1 more source
Release notice - Congenital Anomalies in Canada Data Exploration Tool: latest update on prevalence estimates and temporal trends for congenital anomalies over 15 years (2008-2023). [PDF]
Nelson C +6 more
europepmc +1 more source
We established a spheroid coculture system enabling viable Porphyromonas gingivalis–HNSCC interactions under normoxic conditions. Inhibition of LATS1/2 maintains tumor cells in an undifferentiated state, which may promote spheroid growth and create a more permissive environment for bacterial persistence.
Yurika Nakajima +4 more
wiley +1 more source
DDX3X induces mesenchymal transition of endothelial cells by disrupting BMPR2 signaling
Elevated DDX3X expression led to downregulation of BMPR2, a key regulator of endothelial homeostasis and function. Our co‐immunoprecipitation assays further demonstrated a molecular interaction between DDX3X and BMPR2. Notably, DDX3X promoted lysosomal degradation of BMPR2, thereby impairing its downstream signaling and facilitating endothelial‐to ...
Yu Zhang +7 more
wiley +1 more source
Cluster analysis of social determinants of health and HIV/AIDS knowledge among Peruvian youths using Kohonen's self-organized maps: a data-exploration study based on a Demographic and health survey. [PDF]
Aybar-Flores A +2 more
europepmc +1 more source

