Results 151 to 160 of about 26,367,629 (301)

RECODE - Relational Ecological COrpus for Data Extraction. [PDF]

open access: yesBiodivers Data J
Branco VV   +8 more
europepmc   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

open access: yesMolecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu   +13 more
wiley   +1 more source

Using rule extraction to improve the comprehensibility of predictive models. [PDF]

open access: yes
Whereas newer machine learning techniques, like artifficial neural net-works and support vector machines, have shown superior performance in various benchmarking studies, the application of these techniques remains largely restricted to research ...
Vanthienen, Jan   +2 more
core  

Data mining for activity extraction in video data.

open access: yes, 2008
L'exploration de larges bases de données vidéo est une tâche qui devient possible grâce aux avancées techniques dans la détection et le suivi d'objets. Les méthodes de fouille d'information comme le clustering sont typiquement employées. Celles-ci ont été principalement appliquées pour la segmentation/indexation vidéo mais l'extraction de connaissances
Patino Vilchis, Jose Luis   +3 more
openaire   +2 more sources

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

open access: yesMolecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller   +10 more
wiley   +1 more source

Coupled Hierarchical IR and Stochastic Models for Surface Information Extraction

open access: yes, 1998
We present in this paper a combination of Machine Learning based Information Retrieval (IR) techniques and stochastic language modelling in a hierarchical system that extracts surface information from text.
Surface Information Extraction   +2 more
core  

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