Results 181 to 190 of about 1,950,388 (266)

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

Developing a scalable pipeline for data extraction from clinical letters through resource-efficient prompt engineering

Ong AY, Nguyen Q, Barai I, Engelmann J, Antaki F, Sevgi M, Merle DA, Ju L, Dow E, Zhou Y, Maniatopoulos G, Takwoingi Y, Denniston AK, Keane PA.   +13 more
europepmc   +1 more source

Visualization, Data Extraction, and Multiparametric Analysis of 3D Pancreatic and Colorectal Cancer Cell Lines for High-Throughput Screening. [PDF]

Biomedicines
Trofimov MA, Bulatov IP, Lavrinenko VS, Popov VE, Petrova VS, Bukatin AS, Tyazhelnikov SF.   +6 more
europepmc   +1 more source

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

FEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen, Qianqian Cui, Zhongyun Lan, Yingjun Wang, Shuaiying Zhao, Wenxuan Feng, Yunfeng Liu, Qiting Huang, Dongna Zhang, Jianfeng Xu   +9 more
wiley   +1 more source

Large language models for structured cardiovascular data extraction: a foundation for scalable research and clinical applications. [PDF]

Eur Heart J Digit Health
van der Loo W, van der Valk V, van den Broek T, Atsma D, Staring M, Scherptong R.   +5 more
europepmc   +1 more source

YlmG1 is localized exclusively to the chloroplast envelope membrane and is involved in preprotein translocation in Arabidopsis thaliana

FEBS Open Bio, EarlyView.
Cytosolically synthesized chloroplast preproteins are translocated across the outer and inner envelope membranes through translocons called TOC and TIC, respectively. In green algae and plants, the TIC core is composed of essential membrane proteins, Tic12, Tic20, and Tic214.
Mengyi Li, Xueyang Zhao, Masato Nakai
wiley   +1 more source

Improving reliability and accuracy of structured data extraction using a consensus large-language model approach-a use case description in multiple sclerosis. [PDF]

Front Artif Intell
Poser PL, Klimas R, Luerweg J, Reuter E, Hanefeld C, Gold R, Salmen A, Motte J.   +7 more
europepmc   +1 more source

Iron homeostasis disruption and lipid peroxidation in skeletal muscle during short‐term immobilization

FEBS Open Bio, EarlyView.
14‐day casting‐induced immobilization reduced gastrocnemius muscle mass and increased non‐heme iron and ferritin heavy chain levels. Despite iron accumulation, transferrin receptor 1 and iron regulatory protein 2 were paradoxically upregulated. Lipid peroxidation was elevated without compensatory antioxidant responses.
Haruka Yokogawa, Kazuhiko Higashida, Naoya Nakai   +2 more
wiley   +1 more source

Extracted Data

openaire   +1 more source

Determining patient eligibility for a physical activity referral scheme through EHR data extraction. [PDF]

BMC Med Inform Decis Mak
Rosemeyer J, Trilk JL, Jindal M, Brooks JM, McNulty LK, Stoutenberg M.   +5 more
europepmc   +1 more source