Results 161 to 170 of about 5,167,250 (286)

iPAINT: a general approach tailored to image the topology of interfaces with nanometer resolution.

Nanoscale, 2016
Aloi A, Vilanova N, Albertazzi L, Voets IK.   +3 more
europepmc   +1 more source

The structural assembly switch of cell division protein FtsZ probed with fluorescent allosteric inhibitors. [PDF]

Chem Sci, 2017
Artola M, Ruíz-Avila LB, Ramírez-Aportela E, Martínez RF, Araujo-Bazán L, Vázquez-Villa H, Martín-Fontecha M, Oliva MA, Martín-Galiano AJ, Chacón P, López-Rodríguez ML, Andreu JM, Huecas S.   +12 more
europepmc   +1 more source

Exon 7 splicing of ERα predicts poor prognosis and increases phenotypic heterogeneity in luminal a subtype breast cancer

FEBS Open Bio, EarlyView.
ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui, Taobo Hu, Thomson Christian Husein, Wai Hei Shek, Bingrong Chen, Depeng Wang, Shu Wang, Weichuan Yu, Xiaodan Fan, Mengping Long, Toyotaka Ishibashi   +10 more
wiley   +1 more source

A new function for thermal phase transition-based polymer actuators: autonomous motion on a surface of constant temperature. [PDF]

Chem Sci, 2017
Ge F, Zhao Y.
europepmc   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

Engineering monolayer poration for rapid exfoliation of microbial membranes. [PDF]

Chem Sci, 2017
Pyne A, Pfeil MP, Bennett I, Ravi J, Iavicoli P, Lamarre B, Roethke A, Ray S, Jiang H, Bella A, Reisinger B, Yin D, Little B, Muñoz-García JC, Cerasoli E, Judge PJ, Faruqui N, Calzolai L, Henrion A, Martyna GJ, Grovenor CRM, Crain J, Hoogenboom BW, Watts A, Ryadnov MG.   +24 more
europepmc   +1 more source

Quantitative proteomic analysis reveals different characteristics of bladder cancer cells after exposure to bisphenol A

FEBS Open Bio, EarlyView.
Bisphenol A (BPA), a common chemical in plastics, exerts dual effects on bladder cancer cells: low doses promote growth and migration, while high doses suppress growth and migration. Multi‐omics and bioinformatics reveal BPA acts via MAPK and inflammatory pathways.
Shaomin Niu, Lanlan Li, Wenjuan Jia, Hanzhong Feng, Xiaoquan Yu, Youli Zhao, Fengzhi Yuan, Hui Ding, Junqiang Tian, Yong‐Xing He, Zhiping Wang   +10 more
wiley   +1 more source

Suppression of lung adenocarcinoma migration through organelle alkalization by human lactoferrin – albumin fusion

FEBS Open Bio, EarlyView.
This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia, Masahiro Kimura, Daisuke Kurimoto, Atsushi Sato   +3 more
wiley   +1 more source

From linked open data to molecular interaction: studying selectivity trends for ligands of the human serotonin and dopamine transporter.

Medchemcomm, 2016
Zdrazil B, Hellsberg E, Viereck M, Ecker GF.   +3 more
europepmc   +1 more source

Double quick, double click reversible peptide "stapling". [PDF]

Chem Sci, 2017
Grison CM, Burslem GM, Miles JA, Pilsl LKA, Yeo DJ, Imani Z, Warriner SL, Webb ME, Wilson AJ.   +8 more
europepmc   +1 more source