Results 61 to 70 of about 2,138,949 (260)
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Data Mining Techniques in Analyzing Process Data: A Didactic
Frontiers in Psychology, 2018 Due to increasing use of technology-enhanced educational assessment, data mining methods have been explored to analyse process data in log files from such assessment.
Xin Qiao, Hong Jiao
doaj +1 more source
Data File Standard for Flow Cytometry, Version FCS 3.2. [PDF]
Cytometry A, 2021 Spidlen J +7 more
europepmc +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition
Molecular Oncology, EarlyView.We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li +10 more
wiley +1 more source
Kongzhi Yu Xinxi Jishu, 2018 Data processing in subsystems of CBTC (communication based train control) system are independent at present. As a result, large amount of information interaction between subsystems is not convenient, which wastes a lot of time.
TAN Litian, CHEN Xin, LI Pengdong
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Correction to: Towards a balanced view of the bacterial tree of life
Microbiome, 2017 Correction Following publication of the original article [1], the authors pointed out that the figure shown as figure S1 is actually figure S2 and vice versa. Figure S1 should show the barcharts, and figure S2 should shows the heatmaps.
Frederik Schulz +7 more
doaj +1 more source
Molecular Oncology, EarlyView.We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
GABUNGAN ALGORITMA VERNAM CHIPER DAN END OF FILE UNTUK KEAMANAN DATA
Techno.Com, 2014 Adanya kesamaan fungsi pada metode Kriptografi dan Steganografi untuk mengamankan data, maka makalah ini menggunakan algoritma Vernam Cipher sebagai salah satu algoritma yang popular pada Kriptografi dan End Of File (EOF) pada metode Steganografi ...
Christy Atika Sari, Eko Hari Rachmawanto
doaj