Results 161 to 170 of about 7,552,821 (296)

Clinical Data Flow in Botswana Clinics: Protocol for a Mixed-Methods Assessment. [PDF]

JMIR Res Protoc
Faulkenberry G, Masizana A, Mosesane B, Ndlovu K.   +3 more
europepmc   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

The World Heat Flow Data Collection - 1975 [PDF]

, 2012
et al, ..., Jessop, A M
core  

Combining data flow and control flow computing [PDF]

The Computer Journal, 1982
Philip C. Treleaven, Richard P. Hopkins, Paul W. Rautenbach   +2 more
openaire   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source

Sustainable management of family life and finance in the context of digital capabilities - data flow dynamics. [PDF]

Heliyon
Liu J, Khan M, Liu F.
europepmc   +1 more source

Acoustic Sensor Data Flow for Cultural Heritage Monitoring and Safeguarding. [PDF]

Sensors (Basel), 2019
Kasnesis P, Tatlas NA, Mitilineos SA, Patrikakis CZ, Potirakis SM.   +4 more
europepmc   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Navigating the network: a narrative overview of AMR surveillance and data flow in the United States. [PDF]

Antimicrob Steward Healthc Epidemiol
Robillard DW, Sundermann AJ, Raux BR, Prinzi AM.   +3 more
europepmc   +1 more source