Results 131 to 140 of about 24,275,785 (260)

Structural and biochemical insights into the thermostable esterase Ta0887 from Thermoplasma acidophilum

FEBS Open Bio, EarlyView.
In this study, a novel esterase from the thermoacidophilic archaeon Thermoplasma acidophilum was biochemically and structurally characterized. Our results demonstrate that Ta0887 is a highly thermostable esterase that preferentially hydrolyzes p‐nitrophenyl hexanoate and possesses an α‐helical cap domain that likely contributes to its substrate ...
Alejandro Delgado‐Rey, Miriam Livier Llamas‐García, Gabriela M. Montero‐Morán, Leticia Santos, Samuel Lara‐González   +4 more
wiley   +1 more source

New developments for addressing class imbalance issue in classification tasks

Imbalanced datasets pose a significant challenge in machine learning, often resulting in biased models that inadequately learn from minority class instances.
Matharaarachchi, Surani
core  

A Network Traffic Anomaly Classification Model Based on Self-Attention Mechanism and Convolutional Gated Recurrent Unit

IEEE Access
In the context of accelerated digital transformation, cybersecurity has become a global strategic issue. With the rapid growth of network traffic and the evolving complexity of attack patterns, the stability of information systems and data security face ...
Yulian Li, Yang Su
doaj   +1 more source

Automated detection of intracranial aneurysms using skeleton-based 3D patches, semantic segmentation, and auxiliary classification for overcoming data imbalance in brain TOF-MRA. [PDF]

Sci Rep, 2023
Ham S, Seo J, Yun J, Bae YJ, Kim T, Sunwoo L, Yoo S, Jung SC, Kim JW, Kim N.   +9 more
europepmc   +1 more source

Cell surface CD11c as a neutrophil aging marker molecule

FEBS Open Bio, EarlyView.
Cell surface CD11chi neutrophils were more aged and had better phagocytic function than CD11c−/lo neutrophils. Transcriptomic analysis of CD11chi neutrophils and CD11c−/lo neutrophils in pediatric population showed that the most difference was seen in infants.
Sophia Koutsogiannaki, Fahd Alhamdan, Erik Malm, Marie Bermudez, Samuel Y. Kim, Koichi Yuki   +5 more
wiley   +1 more source

Deployable Deep Learning for Cross-Domain Plant Leaf Disease Detection via Ensemble Learning, Knowledge Distillation, and Quantization

IEEE Access
Accurate leaf disease detection via smartphone-based deep learning holds immense potential for mitigating global crop losses. However, significant deployment challenges persist when transitioning from controlled laboratory environments to real-world ...
Mohammad Junayed Hasan, Suvodeep Mazumdar, Sifat Momen   +2 more
doaj   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

An Integrated Hybrid Deep Learning Framework for Intrusion Detection in IoT and IIoT Networks Using CNN-LSTM-GRU Architecture

Computation
Intrusion detection systems (IDSs) are critical for securing modern networks, particularly in IoT and IIoT environments where traditional defenses such as firewalls and encryption are insufficient against evolving cyber threats.
Doaa Mohsin Abd Ali Afraji, Jaime Lloret, Lourdes Peñalver   +2 more
doaj   +1 more source

Issue of Data Imbalance on Low Birthweight Baby Outcomes Prediction and Associated Risk Factors Identification: Establishment of Benchmarking Key Machine Learning Models With Data Rebalancing Strategies. [PDF]

J Med Internet Res, 2023
Ren Y, Wu D, Tong Y, López-DeFede A, Gareau S.   +4 more
europepmc   +1 more source

Self‐Regulated Learning Meets AI: Reinterpreting Self‐Regulation, Co‐Regulation, and Socially Shared Regulation in Human–AI Interaction

New Directions for Adult and Continuing Education, EarlyView.
ABSTRACT Advancing artificial intelligence (AI) has transformed learning and work, yet higher education and professional development programs have not systematically equipped learners for AI‐prevalent environments. This lack of preparation creates uncertainty regarding control, responsibility, trust, and accountability.
Moon‐Heum Cho, Jerusalem Merkebu
wiley   +1 more source