Results 41 to 50 of about 184,759 (266)

Comparison of Genotype Imputation for SNP Array and Low-Coverage Whole-Genome Sequencing Data

open access: yesFrontiers in Genetics, 2022
Genotype imputation is the term used to describe the process of inferring unobserved genotypes in a sample of individuals. It is a key step prior to a genome-wide association study (GWAS) or genomic prediction.
Tianyu Deng   +5 more
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Imputation Using Training Labels and Classification via Label Imputation

open access: yesIEEE Access
Missing data is a common problem in practice, and various imputation methods have been developed to deal with missing data. However, even though in many cases, the labels are available in the training data, the common practice of imputation usually only ...
Thu Nguyen   +4 more
doaj   +1 more source

MIAEC: Missing Data Imputation Based on the Evidence Chain

open access: yesIEEE Access, 2018
Missing or incorrect data caused by improper operations can seriously compromise security investigation. Missing data can not only damage the integrity of the information but also lead to the deviation of the data mining and analysis.
Xiaolong Xu   +4 more
doaj   +1 more source

Generative Adversarial Networks Assist Missing Data Imputation: A Comprehensive Survey and Evaluation

open access: yesIEEE Access, 2023
Missing data imputation is a technique to deal with incomplete datasets. Since many models and algorithms cannot be applied to data containing missing values, a pre-processing step needs to be performed to remove incomplete data or to estimate the ...
Reza Shahbazian, Sergio Greco
doaj   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

Impute-VSS: A comprehensive web-based visualization and simulation suite for comparative data imputation and statistical evaluation

open access: yesSoftwareX
In today's technological landscape, where data processing forms the backbone of modeling and predictive analytics, data imputation is crucial in filling missing values within datasets using statistical techniques.
Vartul Shrivastava, Shekhar Shukla
doaj   +1 more source

Practical strategies for handling breakdown of multiple imputation procedures

open access: yesEmerging Themes in Epidemiology, 2021
Multiple imputation is a recommended method for handling incomplete data problems. One of the barriers to its successful use is the breakdown of the multiple imputation procedure, often due to numerical problems with the algorithms used within the ...
Cattram D. Nguyen   +2 more
doaj   +1 more source

Column-wise Guided Data Imputation [PDF]

open access: yesProcedia Computer Science, 2017
Abstract This paper investigates data imputation techniques for pre-processing of dataset with missing values. The current literature is mainly focused on the overall accuracy, evaluated estimating the missing values on the dataset at hand, however the predictions can be suboptimal when considering the model performance for each feature.
Alessio Petrozziello, Ivan Jordanov
openaire   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

open access: yesMolecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim   +3 more
wiley   +1 more source

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