Results 31 to 40 of about 4,922,883 (290)

Exposure‐response analyses for selection/confirmation of optimal isatuximab dosing regimen in combination with pomalidomide/dexamethasone treatment in patients with multiple myeloma

open access: yesCPT: Pharmacometrics & Systems Pharmacology, 2022
Isatuximab is an approved anti‐CD38 monoclonal antibody with multiple antitumor modes of action. An exposure‐response (E‐R) analysis using data from patients with relapsed/refractory multiple myeloma (RRMM) enrolled in a phase Ib clinical study who ...
Fatiha Rachedi   +10 more
doaj   +1 more source

Structured Matrix Completion with Applications to Genomic Data Integration [PDF]

open access: yes, 2015
Matrix completion has attracted significant recent attention in many fields including statistics, applied mathematics and electrical engineering. Current literature on matrix completion focuses primarily on independent sampling models under which the ...
Cai, T. Tony, Cai, Tianxi, Zhang, Anru
core   +4 more sources

Population-based surveillance for congenital zika virus syndrome: a latent class analysis of recorded cases from 2015–2018

open access: yesBMC Pregnancy and Childbirth, 2022
Objective This study aims to describe clinical findings and determine the medium-term survival of congenital zika syndrome (CZS) suspected cases. Methods A retrospective cohort study using routine register-based linked data.
Enny S. Paixao   +15 more
doaj   +1 more source

Integration of biological data resources using image object keying. [PDF]

open access: yes, 2003
This paper proposes a novel concept of ‘image object keying'. The work builds on earlier research in this area and shows how the 3D structure of a protein can be retrieved interactively from a gel electrophoresis protein spot.
Khan, Nawaz   +2 more
core   +1 more source

Patterns of multimorbidity and some psychiatric disorders: A systematic review of the literature

open access: yesFrontiers in Psychology, 2022
ObjectiveThe presence of two or more chronic diseases results in worse clinical outcomes than expected by a simple combination of diseases. This synergistic effect is expected to be higher when combined with some conditions, depending on the number and ...
Luis Fernando Silva Castro-de-Araujo   +12 more
doaj   +1 more source

Water, Health, and Social Technologies: One Million Cisterns Programme Case Study

open access: yesAnnals of Global Health
Background: This paper focuses on the impacts of climate change on vulnerable ecosystems and its implications for the health and well-being of populations.
José Firmino de Sousa Filho   +21 more
doaj   +1 more source

Maternal and congenital syphilis in Indigenous Peoples: a scoping review of the worldwide literature

open access: yesInternational Journal for Equity in Health, 2023
Background Syphilis is among the most common sexually transmitted infections worldwide. When it occurs during pregnancy, it can seriously affect the fetus and newborn`s health.
Andrey Moreira Cardoso   +7 more
doaj   +1 more source

Enhanced Data Integration for LabVIEW Laboratory Systems

open access: yes, 2013
Integrating data is a basic concern in many accredited laboratories that perform a large variety of measurements. However, the present working style in engineering faculties does not focus much on this aspect. To deal with this challenge, we developed an
Ionita, Anca Daniela   +3 more
core   +1 more source

The Integration of Coastal Flooding into an ArcFLOOD Data Model [PDF]

open access: yes, 2014
With the impact of global climate change, the speedy, intelligent and accessible dissemination of coastal flood predictions from a number of modelling tools at a range of temporal and spatial scales becomes increasingly important for policy decision ...
Nock, Alison Heidi
core   +2 more sources

A Quality Improvement Initiative to Standardize Pneumocystis jirovecii Pneumonia Prophylaxis in Pediatric Patients With Solid Tumors

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Pediatric patients with extracranial solid tumors (ST) receiving chemotherapy are at an increased risk for Pneumocystis jirovecii pneumonia (PJP). However, evidence guiding prophylaxis practices in this population is limited. A PJP‐related fatality at our institution highlighted inconsistent prescribing approaches and concerns about
Kriti Kumar   +8 more
wiley   +1 more source

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