Results 101 to 110 of about 3,372,497 (294)

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

Molecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan, Irina Primac, Emre Etlioglu, Laurens Debruyne, Ann Janssen, Magy Sallam, Kevin Tabury, Roel Quintens, Wiebren Tjalma, Mohammed Abderrafi Benotmane   +9 more
wiley   +1 more source

Análise rotineira de dados de vigilância em saúde pública: que procedimentos estatísticos utilizar?

Revista de Saúde Pública
Tem havido no país, nos últimos anos, crescente interesse por questões vinculadas à área tradicionalmente denominada vigilância epidemiológica (que se denominou vigilância em saúde pública). Tem-se defendido, em muitas publicações, o ponto de vista que o
Odécio Sanches
doaj  

Usefulness of statistical implicative analysis to identify prognostic factors in patients with breast cancer

Revista Electrónica Dr. Zoilo E. Marinello Vidaurreta, 2019
Background: identifying prognostic factors in patients with breast cancer continues to be a necessity.Objective: to assess the usefulness of statistical implicative analysis to identify the prognostic factors which contribute to the progress of the ...
Surama Pardo-Santana, Nelsa María Sagaró-del-Campo, Larisa Zamora-Matamoros, Dulce María Viltre-Castellanos   +3 more
doaj  

After all, what is the proper use of Kappa statistics in oral health surveys? What don’t manuals tell us?

Brazilian Oral Research
The aim of this study was to elucidate, unclear points of the “Oral Health Survey: basic methods”, of the World Health Organization (WHO), relative to reproducibility (encompassed reliability and agreement) issues during examiners’ calibration.
Andréa Videira ASSAF, Renato Pereira da Silva, Fábio Luiz Mialhe, Antonio Carlos Pereira   +3 more
doaj   +1 more source

PhenoMeter: a metabolome database search tool using statistical similarity matching of metabolic phenotypes for high-confidence detection of functional links

Frontiers in Bioengineering and Biotechnology, 2015
This article describes PhenoMeter, a new type of metabolomics database search that accepts metabolite response patterns as queries and searches the MetaPhen database of reference patterns for responses that are statistically significantly similar or ...
Adam James Carroll, Peng eZhang, Lynne eWhitehead, Sarah eKaines, Guillaume eTcherkez, Murray Ronald Badger   +5 more
doaj   +1 more source

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

Molecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts, Senada Koljenović, Elise Daems, Karolien De Wael, Marc Peeters, Léon C. van Kempen, Greetje Vanhoutte, Karen Zwaenepoel, Timon Vandamme   +8 more
wiley   +1 more source

Analyzing Gensini Score as a Semi-Continuous Outcome

Journal of Tehran University Heart Center, 2016
Background: Investigators frequently encounter continuous outcomes with plenty of values clumped at zero called semi-continuous outcomes. The Gensini score, one of the most widely used scoring systems for expressing coronary angiographic results, is of ...
Homa Kashani, Hojjat Zeraati, Kazem Mohammad, Hamidreza Goodarzynejad, Mahmood Mahmoudi, Saeed Sadeghian, Mohammadali Boroumand   +6 more
doaj  

Implementation of ILLIAC 4 algorithms for multispectral image interpretation [PDF]

Research has focused on the design and partial implementation of a comprehensive ILLIAC software system for computer-assisted interpretation of multispectral earth resources data such as that now collected by the Earth Resources Technology Satellite ...
Donovan, W. E., Ray, R. M., Swain, P. H., Thomas, J. D.   +3 more
core   +1 more source

The influence of ROS1 fusion partners and resistance mechanisms in ROS1‐TKI‐treated non‐small cell lung cancer patients

Molecular Oncology, EarlyView.
This real‐world study of ROS1+ NSCLC highlights fusion diversity, treatment outcomes with crizotinib and lorlatinib, and in vitro experiments with resistance mechanisms. G2032R drives strong resistance to ROS1‐targeted TKIs, especially lorlatinib. Fusion partner location does not affect overall survival to crizotinib or lorlatinib. Findings support the
Fenneke Zwierenga, Christa Dijkhuizen, Patrick Korthuis, Wim Timens, Harry Groen, Jeroen Hiltermann, Anke van den Berg, Lyndsay Drayer, Anthonie van der Wekken   +8 more
wiley   +1 more source

Emerging role of ARHGAP29 in melanoma cell phenotype switching

Molecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster, Melanie Kappelmann‐Fenzl, Anja Katrin Bosserhoff, Nicole Rachinger   +3 more
wiley   +1 more source