Results 161 to 170 of about 1,676,124 (274)

The crystal structure of the Borrelia burgdorferi nicotinamidase BBE22 resolves a long‐standing annotation error

FEBS Open Bio, EarlyView.
The crystal structure of Borrelia burgdorferi nicotinamidase (PncA/BBE22) reveals the correct full‐length protein initiated from a non‐canonical AUU start codon. The structure validates previous biochemical findings and resolves a long‐standing annotation error, demonstrating that the truncated database sequence is structurally incompatible with the ...
Kalvis Brangulis
wiley   +1 more source

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

FEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose, Kotaro Ozaki, Ryohei Kuriyama, Yuka Ikemoto, Kazuhiro Mio, Yuji C. Sasaki, Tatsuya Arai, Sakae Tsuda, Yoichi Shinkai, Masahiro Kuramochi   +9 more
wiley   +1 more source

Statistical methodologies for analyzing a complex sample survey : United States, 1980

The purpose of this report is to provide researchers using the public use data tapes from the National Medical Care Utilization and Expenditure Survey (NMCUES) with guidelines for and illustrations of use of the data on those tapes.

core  

goCluster integrates statistical analysis and functional interpretation of microarray expression data

, 2017
Motivation: Several tools that facilitate the interpretation of transcriptional profiles using gene annotation data are available but most of them combine a particular statistical analysis strategy with functional information.
Chalmel, Frédéric, Wrobel, Gunnar, Primig, Michael   +2 more
core  

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

A Guide to Constructing Indigenous Statistical Spaces for Prevention Science Research. [PDF]

Prev Sci
de la Sierra VQ.
europepmc   +1 more source

The importance of statistical evaluation and experimental-design in the interpretation of data from cancer microdetector studies

, 1980
This article discusses the importance of statistical evaluation and experimental-design in the interpretation of data from cancer microdetector ...
Stimson, W.H., Anderson, J.M., Gettinby, G.   +2 more
core  

Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA

FEBS Open Bio, EarlyView.
PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro, Fernando Lucas Palhano   +1 more
wiley   +1 more source

Passage-Dependent Size Distributions of Human-Derived Cells: Implications for Metabolic Assays. [PDF]

FASEB J
Botte E, Mancini P, Magliaro C, Ahluwalia A.   +3 more
europepmc   +1 more source

The role of statistical methodology in simulation

statistical methods;simulation;operations ...
Kleijnen, J.P.C.
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