Results 51 to 60 of about 1,676,124 (274)

A interpretação estatística como produção de verdades: reflexões éticas

Revista Bioética
Resumo Este ensaio lança um olhar crítico sobre as consequências, na prática do profissional de saúde, da produção de verdades científicas com base em modelos estatísticos.
Dimitri Marques Abramov, Carlos Alberto Mourão Junior   +1 more
doaj   +1 more source

Clarification of Quantitative Intraoral Circumstances with the Community Periodontal Index of Treatment Needs Data using Covariance Structure Analysis [PDF]

Journal of Clinical and Diagnostic Research, 2019
Introduction: Although the severity of periodontal disease is evaluated by various indices, the susceptibility is different among tooth types in the same dentition.
Toshio Kobayashi, Tomonari Suda, Koji Mizutani, Norio Aoyama, Tatsuro Koyanagi, Sae Hayakumo, Yuichi Ikeda, Yuichi Izumi   +7 more
doaj   +1 more source

Intensifying quantitative data analysis and interpretation skills of senior high school students using Statistical Toolbox for Android

This study investigated the effectiveness of the Statistical Toolbox for Android (STA) in enhancing senior high school students’ quantitative data analysis and interpretation skills, compared with the traditional use of calculators. Employing a two-group
Adriel G. Roman, Vennygene M. Sadsad
core   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

FEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga, Toshiki Takahashi, Akiko Kuma, Hiroyuki Kawahara   +3 more
wiley   +1 more source

Prognostic factors in exacerbated chronic obstructive pulmonary disease

Revista Electrónica Dr. Zoilo E. Marinello Vidaurreta, 2021
Background: chronic obstructive pulmonary disease has a high prevalence worldwide. It is important to know the mechanisms that have an influence on the high mortality of the exacerbated form of the disease.Objective: to identify the prognostic factors ...
Iraibis Rodríguez-Pérez, Nelsa María Sagaró-del-Campo, Larisa Zamora-Matamoros, Alejandro Martínez-Álvarez   +3 more
doaj  

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Application of Statistical Tools for Data Analysis and Interpretation in Rice Plant Pathology

Rice Science, 2018
There has been a significant advancement in the application of statistical tools in plant pathology during the past four decades. These tools include multivariate analysis of disease dynamics involving principal component analysis, cluster analysis ...
Parsuram Nayak, Arup Kumar Mukherjee, Elssa Pandit, Sharat Kumar Pradhan   +3 more
doaj   +1 more source