Results 221 to 230 of about 6,318,434 (307)

Comment on: “Polar plumes and fine‐scale coronal structures — On the interpretation of coronal radio sounding data” by Pätzold and Bird [PDF]

, 1998
Richard Woo, S. R. Habbal
openalex   +1 more source

The interpretation of temperature and salinity variables in numerical ocean model output and the calculation of heat fluxes and heat content - ACCESS-CM2 data and code

, 2021
Ryan M. Holmes, Trevor J. McDougall, Paul M. Barker, Rich Pawlowicz, Stephen M. Griffies, Paul J. Durack   +5 more
openalex   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Are standardized conditions needed for correct CGM data interpretation in subjects at early stages of glucose intolerance? [PDF]

Diabetol Metab Syndr
Dimova R, Chakarova N, Tankova T.
europepmc   +1 more source

Tumor mutational burden as a determinant of metastatic dissemination patterns

Molecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal, Andrea Moreno‐Manuel, Miguel Salvadó‐Pertierra, Cristina Santos‐Vivas, Rebeca Sanz‐Pamplona   +4 more
wiley   +1 more source

How to take action beyond ambulatory glucose profile: Latin American expert recommendations on CGM data interpretation. [PDF]

Diabetol Metab Syndr
Calliari LE, Contreras Sepúlveda Á, Coronel-Restrepo N, Kabakian L, Lamounier RN, Picasso E, Proietti A, Ramírez-Rincón A, Yépez-Rodriguez AE.   +8 more
europepmc   +1 more source

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

Molecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon, Dong Young Kim, Yuna Kim, Uk‐Il Kim, Jae‐Sung Kim   +4 more
wiley   +1 more source

The hidden impact of in-source fragmentation in metabolic and chemical mass spectrometry data interpretation. [PDF]

Nat Metab
Giera M, Aisporna A, Uritboonthai W, Siuzdak G.   +3 more
europepmc   +1 more source

Data Sheet 1_Automated interpretation of PD-L1 CPS based on multi-AI models integration strategy in gastric cancer.docx

Ting Han (170267), Meng Zhuo (4489786), Ziyu Song (13242988), Peilin Chen (786396), Shiting Chen (11996513), Wei Zhang (405), Yuanyuan Zhou (389970), Hong Li (20183), Dadong Zhang (605814), Xiaolin Lin (708906), Zebing Liu (13854762), Xiuying Xiao (137669)   +11 more
openalex   +1 more source