Results 231 to 240 of about 6,318,434 (307)

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

Molecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

Molecular Network Analysis in Model and Non-Model Legumes: Challenges in Omics Data Interpretation Across Species, with a Focus on <i>Glycine max, Lupinus albus</i> and <i>Medicago truncatula</i>. [PDF]

Plants (Basel)
Zalzalah N, Bruggink J, Elian M, Lackey S, Wozny JC, Haidar S, Cober ER, Xing T, Samanfar B.   +8 more
europepmc   +1 more source

Lactoferrin treatment activates acetylcholinesterase, decreasing acetylcholine levels in non‐small cell lung cancer (NSCLC) cell culture supernatants, inhibiting cell survival

FEBS Open Bio, EarlyView.
Representation of the suggested mode of action of lactoferrin (Lf) in nonsmall cell lung cancer (NSCLC) A549 cells. Lf induces activation of caspase‐3 by activating p53 and AChE leading to decreased ACh concentrations. In turn, ACh signaling leads to activation of VEGF and AKT and blocking of caspase‐3.
Stuti Goel, Caroline Wozniak, Aya Sabri, Ben Haddad, Brooke Lopo, Alvaro Cobos, Sarah Sarofim, Jeffrey Guthrie, Deborah Heyl, Hedeel Guy Evans   +9 more
wiley   +1 more source

Assessment of salivary microRNA by RT-qPCR: Facing challenges in data interpretation for clinical diagnosis. [PDF]

PLoS One
Van Der Hofstadt M, Cardinal A, Lepeltier M, Boulestreau J, Ouedraogo A, Kahli M, Champigneux P, Molina L, Molina F, Van TNN.   +9 more
europepmc   +1 more source

The Pelotas Basin Oil Province Revealed – New Interpretation from Long Offset 2D Seismic Data

, 2014
Scott A. Bowman, Mike Saunders
openalex   +1 more source

A general model for analysis of linear and hyperbolic enzyme inhibition mechanisms

FEBS Open Bio, EarlyView.
We developed a general enzyme kinetic model that integrates these six basic inhibition mechanism onto a single one. From this model, we deduced a general enzyme kinetic equation that through modulation of simple parameters, γ (the relative inhibitor affinity for two binding sites) and β (the reactivity of the enzyme–substrate–inhibitor complex), is ...
Rafael S. Chagas, Sandro R. Marana
wiley   +1 more source

Virtual Control Groups in Non-clinical Toxicity Studies: Impacts on Toxicologic Clinical Pathology Data Interpretation. [PDF]

Toxicol Pathol
Adedeji AO, Naor AW.
europepmc   +1 more source

Geometric interpretation and data visualisation equivalent describing the DI algorithmic pipeline.

Borjan Milinkovic (21349908), Lionel Barnett (21349911), Olivia Carter (194606), Anil K. Seth (8755419), Thomas Andrillon (6039964)   +4 more
openalex   +1 more source

Overview of molecular signatures of senescence and associated resources: pros and cons

FEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas, Sylvia Vagena, Pavlos Pantelis, Giorgos Theocharous, Russel Petty, Konstantinos Evangelou, Vassilis G. Gorgoulis   +6 more
wiley   +1 more source

Genomic surveillance of SARS-CoV-2 in Taiwan: A perspective on evolutionary data interpretation and sequencing issues. [PDF]

Biomed J
Gong YN, Kuo NY, Yeh TS, Shih SR, Chen GW.   +4 more
europepmc   +1 more source