Results 41 to 50 of about 2,756,498 (272)
Insertion of the FeB cofactor in cNORs lacking metal inserting chaperones
Nitric oxide reductase is an enzyme found in the bacterial denitrification pathway. The NOR active site contains a non‐heme iron, often, but not always inserted with the assistance of chaperones. Here, we study the insertion of FeB in the subfamily of cNORs lacking chaperones and found a putative channel, conserved in the family, perhaps enabling the ...
Sofia Appelgren, Pia Ädelroth
wiley +1 more source
Strengthening pharmacy practice: Development and validation of the Resilience Scale [PDF]
Background/Aim. Despite the demanding nature of their roles in community pharmacies and their critical importance to patient safety, healthcare professionals, including pharmacists, are often not covered by the Resilience Scale. Therefore, the aim of the
Jocić Dragana
doaj +1 more source
Statistical data preparation: management of missing values and outliers [PDF]
Missing values and outliers are frequently encountered while collecting data. The presence of missing values reduces the data available to be analyzed, compromising the statistical power of the study, and eventually the reliability of its results.
Sang Kyu Kwak, Jong Hae Kim
doaj +1 more source
DeepCoDA: personalized interpretability for compositional health data [PDF]
Interpretability allows the domain-expert to directly evaluate the model's relevance and reliability, a practice that offers assurance and builds trust. In the healthcare setting, interpretable models should implicate relevant biological mechanisms independent of technical factors like data pre-processing.
arxiv
Visual and semantic interpretability of projections of high dimensional data for classification tasks [PDF]
A number of visual quality measures have been introduced in visual analytics literature in order to automatically select the best views of high dimensional data from a large number of candidate data projections. These methods generally concentrate on the interpretability of the visualization and pay little attention to the interpretability of the ...
arxiv +1 more source
α2 → 8 polysialic acid elicits poor immunogenicity. Small‐angle scattering shows a supramolecular structure with parallel‐chain binding, although in different forms at μm and mm calcium. The major histocompatibility complex requires molecular weights around 2000 Da to produce antibodies, and 2000 Da polysialic oligomers will bind in these structures ...
Kenneth A. Rubinson
wiley +1 more source
Interpreting Bibliometric Data
Many academic analyses of good practice in the use of bibliometric data address only technical aspects and fail to account for and appreciate user requirements, expectations, and actual practice.
Martin Szomszor+6 more
doaj +1 more source
Venom peptides have shown promise in treating pain. Our study uses computer screening to identify a peptide that targets a sodium channel (NaV1.7) linked to chronic pain. We produced the peptide in the laboratory and refined its design, advancing the search for innovative pain therapies.
Gagan Sharma+8 more
wiley +1 more source
In France, the SOeS⋆ manages a database which contains more than eight million analyses of pesticide concentrations in surface water. In order to interpret these analyses better, we tested methods based on a geographic grouping
Gauroy C., Carluer N.
doaj +1 more source
The power of microRNA regulation—insights into immunity and metabolism
MicroRNAs are emerging as crucial regulators at the intersection of metabolism and immunity. This review examines how miRNAs coordinate glucose and lipid metabolism while simultaneously modulating T‐cell development and immune responses. Moreover, it highlights how cutting‐edge artificial intelligence applications can identify miRNA biomarkers ...
Stefania Oliveto+2 more
wiley +1 more source