Results 41 to 50 of about 24,675,139 (242)

Hydrostatic pressure activates HIF‐1α via β‐catenin to promote stemness in breast cancer cells

open access: yesFEBS Open Bio, EarlyView.
To mimic the elevated intestinal fluid pressure in breast cancers, we loaded human breast cancer cells (MCF‐7, MDA‐MB‐453, and BT‐474) to 50 mmHg hydrostatic pressure. Hydrostatic pressure exposure upregulated HIF‐1α and induced stemness in MCF‐7 and BT‐474 cells.
Da Zhai   +8 more
wiley   +1 more source

Ministry of Justice Synthetic Data First Family Court, England and Wales, 2011-2023

open access: yes
copyright UK Data Service and data collection copyright owner.The Ministry of Justice (MoJ) Data First Synthetic Data Project aims to improve engagement with Data First datasets by making synthetic versions of content available to enable more rapid ...
Ministry of Justice
core   +2 more sources

Digital Inclusion and Social Justice in the Modern Society: the Role of Public-Private Partnerships

open access: yesCхід
The article examines the prerequisites and relevance of the emergence of digital inclusion and social equality. The main opportunities that digitalization provides for various interested groups including society in general are indicated creating the ...
Марина Дєліні   +2 more
doaj   +1 more source

Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1

open access: yesFEBS Open Bio, EarlyView.
The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay   +2 more
wiley   +1 more source

Who is sovereign and how? Informing data sovereignty initiatives beyond borders through analysis of autonomous health movements

open access: yescommunication +1
In response to the increasing harms of large-scale data collection, a range of practices and technologies have been proposed to move towards increased data sovereignty.
Leah Miriam Friedman
doaj   +2 more sources

Learning at the Intersection of Data Literacy and Social Justice

open access: yesEducational Technology & Society, 2022
With growing awareness of, and attention to, the potential of data to inform decisions across contexts, has come an increasing recognition and need to develop data literacy strategies that support people to learn to be critical of data, given this ...
Simon Knight   +2 more
doaj  

Critical big data literacy tools—Engaging citizens and promoting empowered internet usage

open access: yesData & Policy, 2020
Datafied societies need informed public debate about the implications of data science technologies. At present, internet users are often unaware of the potential consequences of disclosing personal data online and few citizens have the knowledge to ...
Ina Sander
doaj   +1 more source

Small RNA pathways in mammalian oocytes

open access: yesFEBS Open Bio, EarlyView.
Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley   +1 more source

Ministry of Justice Synthetic Data First Offender Assessment Dataset, England and Wales, 2011-2023

open access: yes
copyright UK Data Service and data collection copyright owner.The Ministry of Justice (MoJ) Data First Synthetic Data Project aims to improve engagement with Data First datasets by making synthetic versions of content available to enable more rapid ...
Ministry of Justice
core   +2 more sources

Algorithmic emergence? Epistemic in/justice in AI-directed transformations of healthcare

open access: yesFrontiers in Sociology
Moves toward integration of Artificial Intelligence (AI), particularly deep learning and generative AI-based technologies, into the domains of healthcare and public health have recently intensified, with a growing body of literature tackling the ethico ...
Imo Emah, SJ Bennett
doaj   +1 more source

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