Results 241 to 250 of about 25,746,555 (330)

Emergency Department Attendance after Telephone Triage: A Population‐Based Data Linkage Study

Health Services Research, 2018
A. Gibson, D. Randall, D. Tran, Mary Byrne, Anthony Lawler, A. Havard, M. Robinson, Louisa R Jorm   +7 more
semanticscholar   +1 more source

Overview of molecular signatures of senescence and associated resources: pros and cons

FEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas, Sylvia Vagena, Pavlos Pantelis, Giorgos Theocharous, Russel Petty, Konstantinos Evangelou, Vassilis G. Gorgoulis   +6 more
wiley   +1 more source

Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity

FEBS Open Bio, EarlyView.
Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz, Bruna Abreu, Cindy Mendes, Catarina Freitas‐Dias, Filipe Gonçalves, Fernanda Silva, José Ramalho, Saudade André, Vasco D. B. Bonifácio, Jacinta Serpa   +9 more
wiley   +1 more source

Correction: Contact with child protection services during pregnancy: a cross-sectional study using the eLIXIR born in South London, UK maternity-child data linkage. [PDF]

BMC Pregnancy Childbirth
De Backer K, Seed P, Burton S, Montgomery E, Sandall J, eLIXIR-Born in South London Partnership, Easter A.   +6 more
europepmc   +1 more source

Tool for data linkage

Develop a tool that facilitates and partly automatizes data linkages. A tool (for example in R, or Py-thon) will be build. Based on substantial choices made by the researchers, the tool facilitates combin-ing datasets.
openaire   +1 more source

DDX3X induces mesenchymal transition of endothelial cells by disrupting BMPR2 signaling

FEBS Open Bio, EarlyView.
Elevated DDX3X expression led to downregulation of BMPR2, a key regulator of endothelial homeostasis and function. Our co‐immunoprecipitation assays further demonstrated a molecular interaction between DDX3X and BMPR2. Notably, DDX3X promoted lysosomal degradation of BMPR2, thereby impairing its downstream signaling and facilitating endothelial‐to ...
Yu Zhang, Jing Wang, De‐Hui Qian, Yang‐Fan Lv, Tian‐Le Cheng, Da‐Peng Wang, Jing Zhang, Ye Fan   +7 more
wiley   +1 more source

Further Data on Linkage in Rabbits [PDF]

Proceedings of the National Academy of Sciences, 1936
openaire   +2 more sources

Pathogenic Neurofibromatosis type 1 gene variants in tumors of non‐NF1 patients and role of R1276

FEBS Open Bio, EarlyView.
Somatic variants of the neurofibromatosis type 1 (NF1) gene occur across neoplasms without clinical manifestation of the disease NF1. We identified emerging somatic pathogenic NF1 variants and hotspots, for example, at the arginine finger 1276. Those missense variants provide fundamental information about neurofibromin's role in cancer.
Mareike Selig, Swanhild Lohse, Sara Elahi, Nils Hartmann, Stefanie Deckert, Shutian Si, Alexander Desuki, Anja Harder   +7 more
wiley   +1 more source

Recording of HIV diagnosis in mental health records: A data linkage cohort study. [PDF]

PLoS One
Heslin M, Hunt O, Tassie E, Jewell A, King H, Covshoff E, Campbell L, Croxford S, Pittrof R, Sullivan A, Williams J, Newson M, Trevillion K, Smith S, Hughes E, Stewart R.   +15 more
europepmc   +1 more source