Results 241 to 250 of about 593,692 (308)
Mass spectrometry based identification of AMP‐O‐Tris generated by Thermococcus onnurineus Cas10
FEBS Open Bio, EarlyView.Isolated Thermococcus onnurineus Cas10 generates the noncanonical ATP‐derived product AMP‐O‐Tris while in Tris‐containing buffer as identified via mass spectrometry, revealing relaxed nucleophile selectivity under isolated conditions. These findings suggest that multiprotein Csm complex assembly restricts Cas10 reactivity toward canonical cyclic ...
Su‐Jin Lee +6 more
wiley +1 more source
FEBS Open Bio, EarlyView.This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia +3 more
wiley +1 more source
Single-Multiple and Recurrent Pregnancy-Related Complications and Incident Cardiovascular Disease: A Nationwide Data Linkage Study in Wales, UK. [PDF]
J Am Heart AssocAl Bahhawi T +11 more
europepmc +1 more source
Inter-pregnancy interval after caesarean section and subsequent pregnancy outcomes in New South Wales. A data linkage cohort protocol. [PDF]
MethodsXCanty AM +4 more
europepmc +1 more source
Intimate partner violence, multiple mental health conditions and risk of small vulnerable newborn births: a maternity population-based data linkage study. [PDF]
EClinicalMedicineKent L +7 more
europepmc +1 more source