Results 91 to 100 of about 891,248 (273)
Frontiers in Public HealthIntroductionTime banking, known as “Community/Neighborhood Pension,” instantiates a form of co-creation that can provide a new solution to fulfil the unmet social service needs of community members with idle resources, which is a feasible solution to ...
Huifang Jiao +4 more
doaj +1 more source
Consistency Maintenance of State of Management Data in P2P-based Autonomic Network Management [PDF]
arXiv, 2016 Complex Dynamic Networks can be exploited in solving problems where traditional solutions may not be sufficient. The increasing complexity of computer networks imposes problems to the current network management solutions. In this context, network management is an example of a research area that could benefit from the use of CDNs.
arxiv
Adverse prognosis gene expression patterns in metastatic castration‐resistant prostate cancer
Molecular Oncology, EarlyView.We aggregated a cohort of 1012 mCRPC tissue samples from 769 patients and investigated the association of gene expression‐based pathways with clinical outcomes. Loss of AR signaling, high proliferation, and a glycolytic phenotype were independently prognostic for poor outcomes, and an adverse transcriptional feature score incorporating these pathways ...
Marina N. Sharifi +26 more
wiley +1 more source
Data Mining and Its Applications for Knowledge Management: A Literature Review from 2007 to 2012 [PDF]
International Journal of Data Mining & Knowledge Management
Process (IJDKP) Vol.2, No.5, 2012, pp. 13-24, 2012 Data mining is one of the most important steps of the knowledge discovery in databases process and is considered as significant subfield in knowledge management. Research in data mining continues growing in business and in learning organization over coming decades.
arxiv
Transcriptome‐wide analysis of circRNA and RBP profiles and their molecular relevance for GBM
Molecular Oncology, EarlyView.CircRNAs are differentially expressed in glioblastoma primary tumors and might serve as therapeutic targets and diagnostic markers. The investigation of circRNA and RNA‐binding proteins (RBPs) interactions shows that distinct RBPs play a role in circRNA biogenesis and function.
Julia Latowska‐Łysiak +14 more
wiley +1 more source
FSS++ Workshop Report: Handling Uncertainty for Data Quality Management [PDF]
arXiv, 2018 This report describes the results of the eSCF Awareness Workshop on Handling Uncertainty for Data Quality Management - Challenges from Transport and Supply Chain Management that was held on June 5, 2018 in Heeze, The Netherlands. The goal of this workshop was to create and enhance awareness into data quality management issues that are encountered in ...
arxiv
Molecular Oncology, EarlyView.There is an unmet need in metastatic breast cancer patients to monitor therapy response in real time. In this study, we show how a noninvasive and affordable strategy based on sequencing of plasma samples with longitudinal tracking of tumour fraction paired with a statistical model provides valuable information on treatment response in advance of the ...
Emma J. Beddowes +20 more
wiley +1 more source
Molecular Oncology, EarlyView.We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau +11 more
wiley +1 more source
Molecular Oncology, EarlyView.Breast cancer metastasis is associated with myeloid cell dysregulation and the lung‐specific accumulation of tumor‐supportive Gr1+ cells. Gr1+ cells support metastasis, in part, through a CHI3L1‐mediated mechanism, which can be targeted and inhibited with cargo‐free, polymeric nanoparticles.
Jeffrey A. Ma +9 more
wiley +1 more source
Securing Big Data systems, A cybersecurity management discussion [PDF]
arXiv, 2019 This paper explores the essential areas of cybersecurity management for big data systems. Big data platform stems its complexity from being a collection of interrelated non-standardized systems that interact with each other to process large data-sets. This complexity increases the chances of overlooking critical cybersecurity management practices.
arxiv