Results 91 to 100 of about 3,422,128 (268)
Therapeutic Apheresis and Dialysis, EarlyView.ABSTRACT Introduction This final analysis of a multicenter, prospective postmarketing surveillance study evaluated the safety of daprodustat in patients with chronic kidney disease anemia in routine clinical practice in Japan. Methods Patients who initiated daprodustat between September 2020 and July 2022 were registered.
Tadao Akizawa +7 more
wiley +1 more source
Energy Strategy ReviewsThe design of energy policy mixes plays a critical role in low-carbon transitions. While an increasingly diverse and extensive array of policy mixes may enhance systemic transformation, it can also generate policy conflicts that undermine effectiveness ...
Zihan Yin +3 more
doaj +1 more source
Therapeutic Apheresis and Dialysis, EarlyView.ABSTRACT Background Japan has one of the highest dialysis prevalence rates worldwide and a shrinking, aging population. Whether dialysis burden has entered a sustained post‐peak phase or whether recent declines partly reflect pandemic‐related disruptions remains uncertain.
Hatice Şahin +2 more
wiley +1 more source
BIG DATA: CHANGES IN DATA MANAGEMENT
Ekonomski vjesnik : Review of Contemporary Entrepreneurship, Business, and Economic Issues, 2016 We live in a digital environment where everything we do leaves a digital trace. Data are collected from various sources – social network posts, e-mails, sensors, image and video content, search engines, online sales, etc. The biggest reason for this growth of data could be found in technological advancement, since data can be easily and cheaply stored ...
Šebalj, Dario +2 more
openaire +4 more sources
Data management: Managing data as an organisational resource
Acta Commercii, 2003 Managing data as a resource is an important function of information management. Accurate and relevant data is the source of valuable information. By managing data efficiently, sound management decisions can be made. The traditional file environment is not appropriate for managing data; database management systems are the most popular choice for ...
openaire +3 more sources
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Frontiers in MedicineThe performance ceiling of medical AI is largely determined by the quality of its training datasets, yet traditional manual collection and annotation face a triple bottleneck of high cost, embedded bias, and limited scalability.
Tao Tian +3 more
doaj +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
FEBS Letters, EarlyView.Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise +5 more
wiley +1 more source