Results 181 to 190 of about 3,046,624 (266)

Remote Assessment of Ataxia Severity in SCA3 Across Multiple Centers and Time Points

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Spinocerebellar ataxia type 3 (SCA3) is a genetically defined ataxia. The Scale for Assessment and Rating of Ataxia (SARA) is a clinician‐reported outcome that measures ataxia severity at a single time point. In its standard application, SARA fails to capture short‐term fluctuations, limiting its sensitivity in trials.
Marcus Grobe‐Einsler, Vivian Maas, Arian Taheri Amin, Jennifer Faber, Tamara Schaprian, Katharina Hill, Matthis Synofzik, Lisa H. Graf, Heike Jacobi, Manuela Lima, Ana F. Ferreira, Bart P. van de Warrenburg, Ilse H. J. Willemse, Dagmar Timmann, Andreas Thieme, Paola Giunti, Hector Garcia‐Moreno, Magda M. Santana, Jeannette Hübener‐Schmid, Elin H. Davies, Thomas Klockgether   +20 more
wiley   +1 more source

Systematic data management for effective AI-driven decision support systems in robotic rehabilitation. [PDF]

Sci Rep
Tzepkenlis A, Camardella C, Germanotta M, Aprile IG, Mauro MC, Leonardis D, Frisoli A.   +6 more
europepmc   +1 more source

Clustering Algorithm Reveals Dopamine‐Motor Mismatch in Cognitively Preserved Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore the relationship between dopaminergic denervation and motor impairment in two de novo Parkinson's disease (PD) cohorts. Methods n = 249 PD patients from Parkinson's Progression Markers Initiative (PPMI) and n = 84 from an external clinical cohort.
Rachele Malito, Chiara Meneghini, Alice Galli, Luca Gallo, Pierfrancesco Mitrotti, Paola Dimartino, Marianna Inglese, Cinzia Zatti, Alessandro Lupini, Andrea Pilotto, Alessandro Padovani, Micol Avenali, Enza Maria Valente, Cristina Tassorelli, Silvia P. Caminiti   +14 more
wiley   +1 more source

Managing data:

, 1992
Judith J Newton, Mary Lou Melley, Holly Higgins   +2 more
openaire   +1 more source

Editorial: OpenFoodTox: EFSA's open source toxicological database on chemical hazards in food and feed

EFSA Journal, 2017
Jean Lou Dorne, Jane Richardson, Georges Kass, Nikolaos Georgiadis, Mario Monguidi, Luca Pasinato, Stefano Cappe, Hans Verhagen, Tobin Robinson   +8 more
doaj   +1 more source

A human-centered automated machine learning agent with large language models for multimodal data management and analysis. [PDF]

Front Artif Intell
Huang R, Tao S.
europepmc   +1 more source

Diffusion Spectrum Imaging Maps Early Axonal Loss and a Unique Progressive Signal in Neuronal Intranuclear Inclusion Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To delineate specific in vivo white matter pathology in neuronal intranuclear inclusion disease (NIID) using diffusion spectrum imaging (DSI) and define its clinical relevance. Methods DSI was performed on 42 NIID patients and 38 matched controls.
Kaiyan Jiang, Yixiu Pei, Xiaobao Hu, Ying Xiong, Fang Wang, Yanyan Yu, Min Zhu, Dandan Tan, Meihong Zhou, Daojun Hong, Fuqing Zhou   +10 more
wiley   +1 more source

Streamlining large-scale genomic data management: Insights from the UK Biobank whole-genome sequencing data. [PDF]

Cell Genom
Li X, Wood AR, Yuan Y, Zhang M, Huang Y, Hawkes G, Beaumont RN, Weedon MN, Li W, Li X, Lin X, Li Z.   +11 more
europepmc   +1 more source

CX3CL1 in Early Detection of Alzheimer's Disease: Plasma Dynamics Across Age and Disease Stages

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Backgrounds Alzheimer's disease (AD) is characterized by amyloid‐beta plaques, tau tangles, and neuroinflammation. C‐X3‐C motif chemokine ligand 1 (CX3CL1, also known as fractalkine), a neuroimmune chemokine implicated in AD pathogenesis, shows inconsistent alterations in plasma/serum across studies.
Ling Wang, Yujie Liu, Fei Li, Xuelin Li, Lanlan Li, Jie Zhang, Yali Xu   +6 more
wiley   +1 more source

High-content screening (HCS) workflows for FAIR image data management with OMERO. [PDF]

Sci Rep
Massei R, Busch W, Serrano-Solano B, Bernt M, Scholz S, Nicolay EK, Bohring H, Bumberger J.   +7 more
europepmc   +1 more source