Results 181 to 190 of about 4,650,653 (318)

Secure healthcare data management using federated learning, blockchain, and explainable artificial intelligence: a systematic review. [PDF]

Front Digit Health
Bhardwaj T, Sumangali K.
europepmc   +1 more source

Interferon beta drives therapy resistance in a patient‐derived model of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Interferon type 1 (IFN‐1) production and signaling is associated with the acquisition of therapy resistance, following chronic DNA damage, via Interferon‐related DNA damage resistance signature (IRDS) gene expression. An alternative, DNA damage‐independent role of sustained IFN‐1 mediated resistance was identified and characterized by the emergence of ...
Ashlyn Conant, Tise Suzuki, Kiera McGivney, V. S. S. Abhinav Ayyadevara, Sharon Asariah, Jay Deng, Ethan Nyein, Jacqueline Coats, Gary Yu, Yevgeniya J. Ioffe, Christian Hurtz, Juli J. Unternaehrer   +11 more
wiley   +1 more source

Ten simple rules for effective research data management. [PDF]

PLoS Comput Biol
Hassenstein MJ, Jung K.
europepmc   +1 more source

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

Blockchain Technology to Enhance Clinical Data Management in Healthcare: A Systematic Literature Review. [PDF]

Blockchain Healthc Today
Chafik K, Hanine M, Ouaguid A, Alshuhri S.   +3 more
europepmc   +1 more source

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

FEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani, Eiman Y. Ibrahim, Rozalyn L. Rodwin, Leah M. Ferrucci, Kim Blenman, Maryam Lustberg, Barbara E. Ehrlich   +6 more
wiley   +1 more source

Overview of research data management in academic libraries [PDF]

core  

A data migration and integration approach for big data management using linked data. [PDF]

Sci Rep
Sattar H, Al-Khasawneh MA, Shafi UF, Hussain T, Saudagar AKJ, Ul Abideen SZ, Kamal MM, Jahfar Khan SB.   +7 more
europepmc   +1 more source

Identifying gene expression signatures for risk stratification of postoperative adjuvant chemotherapy in colorectal cancer

FEBS Open Bio, EarlyView.
A novel signature integrating genome‐wide analysis with clinical factors predicts recurrence in stage II colorectal cancer and enables a new risk stratification to guide postoperative adjuvant chemotherapy. Clinical risk stratification for postoperative recurrence in patients with pathological stage II (pStage II) colorectal cancer (CRC) is essential ...
Mayuko Otomo, Keisuke Okuno, Shuichi Watanabe, Sakiko Oba, Hiroyasu Kagawa, Masanori Tokunaga, Daisuke Ban, Yusuke Kinugasa   +7 more
wiley   +1 more source

Structured Data Management and Sharing Plan (DMSP) templates outperformed non-structured ones in an institutional implementation of the NIH Data Management and Sharing (DMS) policy. [PDF]

J Clin Transl Sci
Hamidi M, Bikkanuri M, Scott C, Carrizal M, Martinez M, Schorr AN, Qianqian L, Gelfond J, Schmelz J, Potter J, Zozus M.   +10 more
europepmc   +1 more source