Discovery and Targeted Proteomic Studies Reveal Striatal Markers Validated for Huntington's Disease
ABSTRACT Objective Clinical trials for Huntington's disease (HD) enrolling persons before clinical motor diagnosis (CMD) lack validated biomarkers. This study aimed to conduct an unbiased discovery analysis and a targeted examination of proteomic biomarkers scrutinized by clinical validation. Methods Cerebrospinal fluid was obtained from PREDICT‐HD and
Daniel Chelsky +8 more
wiley +1 more source
Impact of Intra-fractional respiratory motion on dose distribution in lattice radiotherapy for liver tumors. [PDF]
Li K, Yin Y, Liu T, Dai T, Zhu J, Li Z.
europepmc +1 more source
ABSTRACT Neuromyelitis Optica Spectrum Disorder (NMOSD) is a chronic autoimmune neuroinflammatory disease, typically characterized by antibodies against aquaporin 4 (AQP4‐IgG) or myelin oligodendrocyte glycoprotein (MOG‐IgG). Simultaneous seropositivity for both antibodies in a single patient is exceedingly rare.
Yeting Luo, Shuhua Xie, Xianghong Liu
wiley +1 more source
Development of Evaluation Criteria for Occupational Health Management Systems: Delphi Study. [PDF]
Song H, Lee J, Sim B, Lee YM, Kim HR.
europepmc +1 more source
Lessons Learned From a Delayed‐Start Trial of Modafinil for Freezing of Gait in Parkinson's Disease
ABSTRACT Objective Freezing of gait (FOG) in people with Parkinson's disease (PwPD) is debilitating and has limited treatments. Modafinil modulates beta/gamma band activity in the pedunculopontine nucleus (PPN), like PPN deep brain stimulation. We therefore tested the hypothesis that Modafinil would improve FOG in PwPD.
Tuhin Virmani +8 more
wiley +1 more source
Measuring Pediatric Disaster Readiness of United States Emergency Departments. [PDF]
Chung S +7 more
europepmc +1 more source
Results from a prospective registry of <sup>18</sup>F-Fluciclovine PET/CT use in prostate cancer management: a cautionary lesson for implementation of PSMA PET. [PDF]
Blinka S +18 more
europepmc +1 more source
Development of a psychological management intervention protocol for Elderly Patients with Chronic Diseases based on the Empowerment Theory: A Delphi study. [PDF]
Su W, Yang H, Fu C, Yang H.
europepmc +1 more source
What Is the Impact of Single-Photon Emission Computed Tomography on the Management of Degenerative Cervical and Lumbar Spine Disease? A Single-Institution Study. [PDF]
Pompliano MJ +10 more
europepmc +1 more source

